Bila Jelena, Andjelić Bosko, Bodrozić Jelena, Jaković Ljubomir, Jovanović Maja Perunicić, Vidović Ana, Todorović Milena, Mihaljević Biljana
Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia.
Vojnosanit Pregl. 2013 Oct;70(10):972-5. doi: 10.2298/vsp1310972b.
Special entities like solitary bone plasmocytoma (SBP) or extramedullary plasmacytoma (EMP) can be found in a less than 5% of patients with plasma cell disorders. EMP of the tongue represents very rare localization of the head and neck plasmacytoma.
We report a case of 78-years-old woman who developed EMP of the tongue base detected by the magnetic resonance imaging (MRI) of the head and neck region. Immunohistochemical profile of the tumor tissue biopsy (CD38, IgG, kappa positivity) indicated diagnosis of EMP. The diagnosis was established with additional staging which confirmed the absence of other manifestation of the disease. The patient was treated with 40 Gy of radiotherapy in 20 doses resulting in the achievement of the complete remission of the disease. This case was discussed with the reference to the literature.
EMP of the tongue base is a very rare entity of plasma cell dyscrasias. Appropriate irradiation results in the achievement of a long-term remission and a potential cure of the disease.
在不到5%的浆细胞疾病患者中可发现孤立性骨浆细胞瘤（SBP）或髓外浆细胞瘤（EMP）等特殊实体。舌部EMP是头颈部浆细胞瘤非常罕见的定位。
我们报告一例78岁女性，通过头颈部区域的磁共振成像（MRI）检测到舌根EMP。肿瘤组织活检的免疫组织化学特征（CD38、IgG、κ阳性）提示EMP诊断。通过进一步分期确诊，证实无疾病的其他表现。患者接受了20次共40 Gy的放射治疗，疾病实现完全缓解。结合文献对该病例进行了讨论。
舌根EMP是浆细胞发育异常中非常罕见的一种实体。适当的放疗可实现疾病的长期缓解并有可能治愈。
