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足月妊娠中使用普洛施进行宫颈成熟及引产的效果评估。

Evaluation of Propess outcomes for cervical ripening and induction of labour in full-term pregnancy.

作者信息

Chen W, Zhou Y, Pu X, Xiao C

机构信息

Department of Obstetrics, Shanghai Changning Maternity and Infant Health Hospital , Shanghai , China.

出版信息

J Obstet Gynaecol. 2014 Apr;34(3):255-8. doi: 10.3109/01443615.2013.853730. Epub 2013 Dec 6.

Abstract

This study was to investigate the efficiency and safety of vaginal Propess as a methodology for cervical ripening and labour induction in full-term pregnant patients. Women at term with a Bishop's score of < 6 and without any contraindications, to vaginal delivery, or the use of prostaglandin or oxytocin in induction of labour, were divided into three groups: oxytocin group (n = 59), intact membranes (Propess I group; n = 58) and natural rupture (Propess R group; n = 52) groups. The main outcome measures, including change in Bishop's score, induction to delivery interval, total delivery time, rate of vaginal delivery, fetal outcome and maternal complications during induction, were recorded. In the Propess groups, the Bishop's score and rate of vaginal delivery were significantly higher while the induction to delivery interval and total delivery time were much shorter, as compared with oxytocin patients (p < 0.01). There were no significant differences in fetal and maternal outcome during induction between the Propess groups and oxytocin group (p > 0.05). In addition, there were no significant differences of Bishop's score, rate of vaginal delivery, induction to delivery interval and total delivery time between the Propess I group and Propess R group (p > 0.05). Propess is an effective and safe approach to promote cervical ripening and be successfully used in induction of labour.

摘要

本研究旨在探讨阴道使用普贝生作为足月妊娠患者促宫颈成熟及引产方法的有效性和安全性。将足月、Bishop评分<6分、无阴道分娩禁忌证、未使用前列腺素或缩宫素引产的孕妇分为三组:缩宫素组(n = 59)、胎膜完整(普贝生I组;n = 58)和胎膜自然破裂(普贝生R组;n = 52)组。记录主要观察指标,包括Bishop评分变化、引产至分娩间隔时间、总分娩时间、阴道分娩率、胎儿结局及引产期间的母体并发症。与缩宫素组患者相比,普贝生组的Bishop评分和阴道分娩率显著更高,而引产至分娩间隔时间和总分娩时间则短得多(p < 0.01)。普贝生组与缩宫素组引产期间的胎儿和母体结局无显著差异(p > 0.05)。此外,普贝生I组与普贝生R组在Bishop评分、阴道分娩率、引产至分娩间隔时间和总分娩时间方面无显著差异(p > 0.05)。普贝生是促进宫颈成熟并成功用于引产的一种有效且安全的方法。

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