Academy of Medical Sciences of Croatia.
Clin Dermatol. 2014 Jan-Feb;32(1):125-30. doi: 10.1016/j.clindermatol.2013.05.034.
Perioral dermatitis is a relatively common inflammatory facial skin disorder that predominantly affects women. It is rarely diagnosed in children. A typical perioral dermatitis presentation involves the eruption of papules and pustules that may recur over weeks to months, occasionally with fine scales. The differential diagnosis includes seborrheic dermatitis, systemic lupus erythematosus, acne vulgaris, lupus miliaris disseminatus faciei, polymorphous light eruption, steroid-induced rosacea, granulomatous perioral dermatitis, contact dermatitis (allergic and irritant), and even basal cell carcinoma. The histopathology is similar to that of rosacea, with a perivascular and perifollicular lymphohistiocytic infiltrate and sebaceous hyperplasia. The etiology of perioral dermatitis is unknown, but the uncritical use of topical corticosteroids often precedes skin lesions. Physical sunscreens with high sun protection factors may cause perioral dermatitis in children.
口周皮炎是一种相对常见的炎症性面部皮肤疾病，主要影响女性。儿童很少被诊断出患有该病。典型的口周皮炎表现为丘疹和脓疱的发作，可能会在数周到数月内反复发作，偶尔会出现细鳞屑。鉴别诊断包括脂溢性皮炎、系统性红斑狼疮、寻常痤疮、播散性粟粒状狼疮、多形性日光疹、类固醇性酒渣鼻、肉芽肿性口周皮炎、接触性皮炎（变应性和刺激性），甚至基底细胞癌。组织病理学类似于酒渣鼻，表现为血管周围和毛囊周围淋巴组织细胞浸润和皮脂腺增生。口周皮炎的病因不明，但过度使用局部皮质类固醇激素常导致皮肤病变。高防晒因子的物理防晒霜可能会导致儿童出现口周皮炎。
