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有症状子宫肌瘤的非手术治疗方法。物理方法:选择性栓塞术

[Non-surgical approach for symptomatic fibroids. Physical methods: selective embolization].

作者信息

Tarriel Josep Estadella, Moreno Cristina Soler, Ajenjo Marta Campillo, Vara Rubén Guerrero

机构信息

Servicio de Obstetricia y Ginecología, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, España.

出版信息

Med Clin (Barc). 2013 Jul;141 Suppl 1:17-21. doi: 10.1016/S0025-7753(13)70048-4.

DOI:10.1016/S0025-7753(13)70048-4
PMID:24314563
Abstract

The approach to symptomatic uterine fibroids has seen a marked evolution in recent years thanks to the emergence of minimally invasive techniques that allow for uterine preservation. Selective uterine artery embolization (UAE) consists of the complete occlusion of the 2 uterine arteries with embolic particles in order to produce ischemic necrosis of the fibroids without permanently affecting the normal uterine tissue. This technique significantly reduces the amount of bleeding and causes a reduction in uterine volume at 3 months postprocedure, which is maintained over time, allowing for 70% of patients to avoid surgery. Moreover, UAE entails shorter surgical times, reduced hospital stays and fewer days needed to return to work when compared with traditional surgical techniques (hysterectomy and fibroidectomy), without any differences in the quality-of-life scales at 5 years. UAE should therefore be included in the therapeutic options offered to patients with symptomatic fibroid uteri.

摘要

近年来,由于出现了能够保留子宫的微创技术,有症状子宫肌瘤的治疗方法发生了显著演变。选择性子宫动脉栓塞术(UAE)是用栓塞颗粒完全闭塞两条子宫动脉,以使肌瘤发生缺血性坏死,而不会永久性影响正常子宫组织。该技术可显著减少出血量,并在术后3个月时使子宫体积缩小,且这种缩小会随时间持续存在,使得70%的患者可避免手术。此外,与传统手术技术(子宫切除术和肌瘤切除术)相比,UAE的手术时间更短、住院时间缩短且恢复工作所需天数更少,在5年时生活质量量表方面没有差异。因此,UAE应纳入为有症状子宫肌瘤患者提供的治疗选择中。

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