Lamberth F, Guilbert P, Gaillot-Petit N, Champagne C, Looten-Vieren L, Nguyen T D
Département de radiothérapie, institut Jean-Godinot, rue du Général-Koenig, 51100 Reims, France.
Unité de radiophysique médicale, institut Jean-Godinot, rue du Général-Koenig, 51100 Reims, France.
Cancer Radiother. 2014 Jan;18(1):7-14. doi: 10.1016/j.canrad.2013.07.148. Epub 2013 Dec 5.
To evaluate the dosimetric gain obtained in either the planning target volume or organs at risk coverage by the use of intensity-modulated radiation therapy in some particular postoperative breast cancers.
Prospective dosimetric comparison between monoisocentric conformal radiotherapy and intensity-modulated radiation therapy in nine patient files.
Using intensity-modulated radiation therapy was shown to improve in each case, at least one conformity, homogeneity, and coverage index either for planning target volumes or for organs at risk. Intensity-modulated radiation therapy was therefore always chosen rather than conformal monoisocentric radiotherapy.
Indications to retain intensity-modulated radiation therapy would consist of bilateral lesions, pectus excavatum, past thoracic irradiation (Hodgkin's disease) and complex volumes in obese or overweight patients.
评估在某些特定的术后乳腺癌中,使用调强放射治疗在计划靶区或危及器官覆盖方面所获得的剂量学增益。
对9份患者病历进行单中心适形放疗与调强放射治疗之间的前瞻性剂量学比较。
结果显示,在每种情况下,使用调强放射治疗至少能改善计划靶区或危及器官的一项适形性、均匀性和覆盖指数。因此,总是选择调强放射治疗而非单中心适形放疗。
保留调强放射治疗的指征包括双侧病变、漏斗胸、既往胸部放疗(霍奇金病)以及肥胖或超重患者的复杂靶区。