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1320nm 掺钕钇铝石榴石激光治疗大隐及小隐静脉曲张:1171 例回顾性病例系列研究

Endovenous laser ablation of the great and short saphenous veins with a 1320-nm neodymium:yttrium-aluminum-garnet laser: retrospective case series of 1171 procedures.

机构信息

Private practice, Laguna Beach, California.

Scripps Clinic Vein Center, San Diego, California.

出版信息

J Am Acad Dermatol. 2014 Feb;70(2):326-31. doi: 10.1016/j.jaad.2013.10.005. Epub 2013 Dec 4.

DOI:10.1016/j.jaad.2013.10.005
PMID:24314878
Abstract

BACKGROUND

Venous insufficiency is a common medical condition affecting up to 50.5% of women and 30.1% of men. Endovenous laser ablation is a minimally invasive procedure that safely and effectively treats reflux involving the great and short saphenous veins.

OBJECTIVE

We sought to present safety and efficacy data of 1171 endovenous laser ablations using the Scripps Clinic endovenous laser therapy (EVLT) protocol.

METHODS

We conducted an institutional review board-approved, retrospective chart analysis of 1171 endovenous laser ablations performed from March 2007 until February 2011 treated at Scripps Clinic with the 1320-nm neodymium:yttrium-aluminum-garnet laser with 1-month, 6-month, 1-year, and 2-year follow-up data.

RESULTS

Our current overall experience is greater than 2000 EVLT procedures. The mean follow-up for this case series of 1171 EVLT procedures (1066 great saphenous veins and 105 short saphenous veins) is 11.4 months with an overall closure success rate of 99.9% for patients not lost to follow-up. There has been no incidence of deep vein thrombosis, permanent nerve damage, or pulmonary embolism related to laser ablation.

LIMITATIONS

Retrospective chart analysis, investigator bias, patients lost to follow-up, and lack of quality-of-life assessment are limitations.

CONCLUSION

EVLT using a 1320-nm neodymium:yttrium-aluminum-garnet laser appears to be a viable option for venous insufficiency and venous ulceration unresponsive to conservative treatment.

摘要

背景

静脉功能不全是一种常见的医学病症,影响多达 50.5%的女性和 30.1%的男性。静脉内激光消融术是一种微创程序,可以安全有效地治疗大隐静脉和小隐静脉的反流。

目的

我们旨在展示使用 Scripps 诊所静脉内激光治疗 (EVLT) 方案进行的 1171 例静脉内激光消融术的安全性和疗效数据。

方法

我们进行了一项机构审查委员会批准的回顾性图表分析,对 2007 年 3 月至 2011 年 2 月在 Scripps 诊所接受 1320nm 钕:钇 - 铝 - 石榴石激光治疗的 1171 例静脉内激光消融术进行了研究,随访时间为 1 个月、6 个月、1 年和 2 年。

结果

我们目前的总体经验超过 2000 例 EVLT 手术。本 1171 例 EVLT 手术(1066 例大隐静脉和 105 例小隐静脉)的平均随访时间为 11.4 个月,未失访患者的总体闭合成功率为 99.9%。没有发生与激光消融相关的深静脉血栓形成、永久性神经损伤或肺栓塞。

局限性

回顾性图表分析、研究者偏倚、患者失访以及缺乏生活质量评估是本研究的局限性。

结论

使用 1320nm 钕:钇 - 铝 - 石榴石激光的 EVLT 似乎是一种可行的选择,适用于对保守治疗无反应的静脉功能不全和静脉溃疡。

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