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空肠游离皮瓣用于头颈部癌症患者咽缺损的重建——伯明翰经验

Jejunal free flap for reconstruction of pharyngeal defects in patients with head and neck cancer-the Birmingham experience.

作者信息

Walker Rachel J, Parmar Satyesh, Praveen Prav, Martin Tim, Pracy Paul, Jennings Chris, Simms Malcolm

机构信息

University Hospital Birmingham, Core Surgical Trainee (OMFS), United Kingdom.

University Hospital Birmingham, Consultant Oral & Maxillofacial Surgeon, United Kingdom.

出版信息

Br J Oral Maxillofac Surg. 2014 Feb;52(2):106-10. doi: 10.1016/j.bjoms.2013.11.005. Epub 2013 Dec 5.

Abstract

We retrospectively audited operative complications, success of flaps, and speech and swallowing outcomes in patients with head and neck cancer who had reconstruction with jejunal free tissue transfer to the pharynx. A total of 104 patients had jejunal free flaps between 1987 and 2009 at University Hospital, Birmingham. Management was by a multidisciplinary team, and the same vascular surgeon did all the anastomoses. We investigated the relations between patients, operative factors, and postoperative complications, and noted the ischaemic time of the flaps and coexisting conditions of the patients. Outcomes measured included initial and final survival rates of flaps, donor and recipient site complications, and speech and swallowing outcomes on discharge and up to 2 years postoperatively. Of the 104 patients, 14 (13%) had initial flap complications but overall flap survival was 97%. A total of 11 (11%) patients developed a fistula at a mean of 15 days postoperatively and 11 (11%) had minor donor site complications. A total of 95 (91%) were able to resume oral diet on discharge. Of the 44 who were followed up on discharge, 32 (73%) were able to maintain oral intake at 2 years and 31 (70%) could use their voice in everyday situations. The jejunal free flap enables the tumour to be removed, and reconstruction and restoration of function to be done in a single operation using tissue that is versatile. The operation is associated with low morbidity at the donor and recipient sites, and results in good speech and swallowing outcomes. The flap can also be used to reconstruct pharyngolaryngeal defects.

摘要

我们回顾性审计了接受空肠游离组织转移至咽部进行重建的头颈癌患者的手术并发症、皮瓣成功率以及言语和吞咽结果。1987年至2009年期间,伯明翰大学医院共有104例患者接受了空肠游离皮瓣手术。治疗由多学科团队进行,且所有吻合手术均由同一位血管外科医生完成。我们研究了患者、手术因素与术后并发症之间的关系,并记录了皮瓣的缺血时间以及患者的并存疾病情况。测量的结果包括皮瓣的初始和最终存活率、供体和受体部位并发症,以及出院时和术后长达2年的言语和吞咽结果。104例患者中,14例(13%)出现了初始皮瓣并发症,但皮瓣总体存活率为97%。共有11例(11%)患者在术后平均15天出现瘘管,11例(11%)出现轻微的供体部位并发症。共有95例(91%)患者在出院时能够恢复经口饮食。在出院后接受随访的44例患者中,32例(73%)在2年时能够维持经口进食,31例(70%)在日常情况下能够发声。空肠游离皮瓣能够在一次手术中切除肿瘤,并利用多功能组织进行重建和功能恢复。该手术在供体和受体部位的发病率较低,并能带来良好的言语和吞咽结果。该皮瓣还可用于重建咽喉部缺损。

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