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围生期缺氧和窒息时循环调节的病理生理学

[Pathophysiology of circulatory regulation in hypoxia and asphyxia in the perinatal period].

作者信息

Schwartze H

出版信息

Zentralbl Gynakol. 1986;108(17):1033-8.

PMID:2431559
Abstract

Asphyxia is defined as hypoxia with hypercapnia; the physiology and pathophysiology of the O2-saturation-curve in maternal and fetal blood is given. Recent results about the redistribution of the cardiac output in chronically instrumented fetal lambs under the conditions of asphyxia, hypoxia and acidosis are reported. The life-threatening consequences of ischaemic situations in the regional circulations for liver, gut, kidney and lung are described, particularly in the newborn. It is stressed that in asphyxiated babies which show circulatory and/or cerebral disturbances, further organ functions (e.g. respiration, excretion) may be seriously damaged.

摘要

窒息被定义为伴有高碳酸血症的低氧血症;文中给出了母体和胎儿血液中氧饱和度曲线的生理学和病理生理学情况。报告了关于慢性植入仪器的胎羊在窒息、低氧血症和酸中毒情况下心输出量重新分布的最新研究结果。描述了局部循环中肝脏、肠道、肾脏和肺部缺血情况危及生命的后果,尤其是在新生儿中。强调在出现循环和/或脑部紊乱的窒息婴儿中,其他器官功能(如呼吸、排泄)可能会受到严重损害。

相似文献

1
[Pathophysiology of circulatory regulation in hypoxia and asphyxia in the perinatal period].围生期缺氧和窒息时循环调节的病理生理学
Zentralbl Gynakol. 1986;108(17):1033-8.
2
Cerebral oxygen consumption during asphyxia in fetal sheep.胎儿绵羊窒息时的脑氧消耗
J Dev Physiol. 1990 Sep;14(3):131-7.
3
Maternal halothane anesthesis reduces cerebral blood flow in the acidotic sheep fetus.母体氟烷麻醉可降低酸中毒绵羊胎儿的脑血流量。
Anesth Analg. 1980 Jan;59(1):35-9.
4
Neurologic aspects of perinatal asphyxia.围产期窒息的神经学方面
Pediatr Ann. 1978 Dec;7(12):15-31.
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Fetal circulatory responses to oxygen lack.胎儿对缺氧的循环反应。
J Dev Physiol. 1991 Oct;16(4):181-207.
6
Redistribution of fetal circulation during repeated asphyxia in sheep: effects on skin blood flow, transcutaneous PO2, and plasma catecholamines.绵羊反复窒息期间胎儿循环的重新分布:对皮肤血流、经皮氧分压和血浆儿茶酚胺的影响。
J Dev Physiol. 1987 Feb;9(1):41-55.
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Endotoxemia severely affects circulation during normoxia and asphyxia in immature fetal sheep.内毒素血症严重影响未成熟胎羊在常氧和窒息状态下的循环。
J Soc Gynecol Investig. 2001 May-Jun;8(3):134-42.
8
[Circulation and energy supply to the fetal brain in hypoxia: relation to early childhood brain damage].[缺氧时胎儿脑循环与能量供应:与儿童早期脑损伤的关系]
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[Effect of oxygen starvation on fetal and neonatal development].[缺氧对胎儿及新生儿发育的影响]
Feldsher Akush. 1977 Sep;42(9):24-30.
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