识别遗传性结直肠癌。

Recognizing hereditary colorectal cancer.

作者信息

Kline Rochelle Paris

机构信息

Rochelle Paris Kline practices in the Department of Surgery, at the University of Pittsburgh Medical Center in Pittsburgh, with an emphasis on surgical oncology and colorectal surgery. The author has indicated no relationships to disclose relating to the content of this article.

出版信息

JAAPA. 2014 Jan;27(1):14-8. doi: 10.1097/01.JAA.0000438527.61644.75.

DOI:10.1097/01.JAA.0000438527.61644.75

PMID:24317327

Abstract

Colorectal cancer is the second-leading cause of cancer death in the United States. About 25% of patients have a personal or family history that suggests a hereditary colorectal cancer syndrome. This article describes the clinical and pathological characteristics of hereditary colorectal cancer, appropriate screening tests, and when to refer patients to a genetic counselor.

摘要

结直肠癌是美国癌症死亡的第二大主要原因。约25%的患者有提示遗传性结直肠癌综合征的个人或家族病史。本文描述了遗传性结直肠癌的临床和病理特征、合适的筛查测试，以及何时将患者转诊给基因咨询师。