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一项针对精神分裂症患者的适应型疾病管理和康复计划的随机对照试验,这些患者正等待从精神病院出院。

A randomized controlled trial of an adapted Illness Management and Recovery program for people with schizophrenia awaiting discharge from a psychiatric hospital.

机构信息

Department of Nursing, College of Medicine, National Cheng Kung University.

出版信息

Psychiatr Rehabil J. 2013 Dec;36(4):243-9. doi: 10.1037/prj0000013.

DOI:10.1037/prj0000013
PMID:24320832
Abstract

OBJECTIVE

Most research on the Illness Management and Recovery (IMR) program for people with severe mental illnesses has focused on individuals with stable symptoms living in the community, with less attention to persons being treated in an inpatient setting. We evaluated the feasibility and effects of an IMR program adapted for individuals with schizophrenia who were awaiting discharge into the community.

METHOD

A randomized controlled trial was conducted at 2 hospitals in Taiwan to compare the adapted IMR program with treatment as usual (TAU). Ninety-seven individuals with schizophrenia were randomized to the adapted IMR program or TAU. Four outcome indicators including illness-management knowledge, attitudes toward medication, insight, and symptoms were assessed at baseline, posttreatment, and at a 1-month follow-up following discharge from the hospital.

RESULTS

Participants in the adapted IMR group showed significantly greater improvements at posttreatment and 1-month follow-up in illness-management knowledge, attitudes toward medication, insight, and negative symptoms on the Brief Psychiatric Rating Scale (BPRS) than individuals in the TAU group. There were no significant differences between the 2 groups on other subscales of the BPRS.

CONCLUSIONS AND IMPLICATIONS FOR PRACTICE

This is the first controlled evaluation of a version of the IMR program in an East Asian culture, and the first to evaluate it in an acute care inpatient setting. Our findings support the feasibility and potential benefits of implementing an adapted IMR program, focused on the prevention of relapses and rehospitalizations, during the discharge period of an inpatient treatment stay to prepare individuals to reenter the community.

摘要

目的

大多数关于严重精神疾病患者的疾病管理和康复(IMR)计划的研究都集中在社区中症状稳定的个体上,而对在住院环境中接受治疗的个体关注较少。我们评估了针对即将出院进入社区的精神分裂症患者的 IMR 计划的适应性及其效果。

方法

在台湾的 2 家医院进行了一项随机对照试验,比较了适应性 IMR 计划与常规治疗(TAU)。将 97 名精神分裂症患者随机分配到适应性 IMR 计划或 TAU 组。在基线、治疗后和出院后 1 个月随访时评估了 4 个结局指标,包括疾病管理知识、对药物的态度、洞察力和症状。

结果

与 TAU 组相比,适应性 IMR 组在治疗后和出院后 1 个月随访时,在疾病管理知识、对药物的态度、洞察力和简明精神病评定量表(BPRS)的阴性症状方面的改善更为显著。2 组在 BPRS 的其他分量表上无显著差异。

结论和对实践的意义

这是在东亚文化中对 IMR 计划的一个版本进行的首次对照评估,也是首次在急性住院环境中对其进行评估。我们的研究结果支持在住院治疗期间的出院阶段实施适应性 IMR 计划的可行性和潜在益处,该计划侧重于预防复发和再住院,以帮助个体重新进入社区。

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