Itagaki Michael W
Section of Interventional Radiology, EvergreenHealth Medical Center, 12040 NE 128th St, Kirkland, WA, 98034, USA,
Cardiovasc Intervent Radiol. 2014 Aug;37(4):1073-7. doi: 10.1007/s00270-013-0816-7. Epub 2013 Dec 10.
Particle embolotherapy for liver cancers, such as chemoembolization and yttrium-90 radioembolization, depends on microcatheter selection of the treatment vessel for injection of the embolic. Individually selecting vessels with a microcatheter can be time-consuming and difficult, especially when multiple branches are present in the treatment zone. This article describes a technique to perform an "inverse" embolization-protection of the selected vessel and embolization of the unselected vessels-a technique that has not yet been described.
Two cases of hepatic chemoembolization that would require subselection of multiple branch vessels using conventional technique are reported. In both cases the proper hepatic artery was selected with a soft, nondissecting neurovascular guide catheter. The nontarget hepatic vessel was selected with a neurovascular microcatheter occlusion balloon, and the balloon was inflated to protect that vessel. Embolization to multiple target vessels was then achieved by way of a single injection through the guide catheter.
Both procedures were technically successful without complication. Postembolization angiography confirmed normal parenchymal enhancement in the protected zone and expected paucity of enhancement in the treated zone.
Temporary distal balloon occlusion is a useful technique to treat multiple artery branches with a single injection in cases where individual selection of the branches is difficult or time-consuming. Further study of this technique is warranted.
肝癌的粒子栓塞治疗,如化疗栓塞和钇-90放射性栓塞,取决于用于注射栓塞剂的治疗血管的微导管选择。使用微导管逐个选择血管可能既耗时又困难,尤其是当治疗区域存在多个分支时。本文描述了一种对选定血管进行“逆向”栓塞保护并对未选定血管进行栓塞的技术——一种尚未被描述过的技术。
报告了2例需要使用传统技术对多个分支血管进行亚选择的肝化疗栓塞病例。在这两个病例中,均使用柔软、无切割的神经血管引导导管选择肝固有动脉。使用神经血管微导管封堵球囊选择非目标肝血管,并使球囊膨胀以保护该血管。然后通过引导导管单次注射对多个目标血管进行栓塞。
两个手术在技术上均获成功,无并发症发生。栓塞后血管造影证实保护区实质强化正常,治疗区强化预期减少。
在难以或耗时逐个选择分支的情况下,临时远端球囊封堵是一种通过单次注射治疗多个动脉分支的有用技术。有必要对该技术进行进一步研究。