Yabuki Hiroshi, Tabata Toshiharu, Sugawara Takafumi, Miyamoto Akira, Fukaya Ken, Saito Tsutomu, Fujimura Shigefumi
Department of Thoracic Surgery, Tohoku Pharmaceutical University Hospital, Sendai, Japan.
Kyobu Geka. 2013 Dec;66(13):1167-70.
The patients was 63-year-old man. He had a chest abnormally shadow pointed out in examination of March, 2012 and referred to our hospital for a close inspection. The chest computed tomography(CT)revealed a mass shadow of 60 mm in left lung. Bronchoscopic examination was done and it was diagnosed as non-small-cell lung cancer by cytology. The clinical stage was cT2bN1M0 and video-assistedthoracic surgery (VATS) left pneumonectomy with mediastinal lymph node dissection was performed. A lot of neoplastic cells which contained melanin in cytoplasm were recognized by pathology and the diagnosis of malignant melanoma was comfirmed. Lymph node metastasis were recognized in #10, #11, #12 and the pathological stage of a disease was pT2bN1M0, pStage IIB. Further examination to find another lesion after surgery was in vain suggesting primary site to be left lung. A adjuvant chemotherapy has not been done. Surgical resection of primary pulmonary malignant melanoma is reported with reference to literatures.
患者为一名63岁男性。2012年3月检查时发现胸部有异常阴影,遂转诊至我院进行详细检查。胸部计算机断层扫描(CT)显示左肺有一个60毫米的肿块阴影。进行了支气管镜检查,通过细胞学诊断为非小细胞肺癌。临床分期为cT2bN1M0,遂行电视辅助胸腔镜手术(VATS)左肺切除术并进行纵隔淋巴结清扫。病理检查发现许多细胞质中含有黑色素的肿瘤细胞,确诊为恶性黑色素瘤。在第10、11、12组发现淋巴结转移,疾病的病理分期为pT2bN1M0,pIIB期。术后进一步检查未发现其他病变,提示原发部位为左肺。未进行辅助化疗。参考文献报道了原发性肺恶性黑色素瘤的手术切除情况。