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原发性肺恶性黑色素瘤

[Primary pulmonary malignant melanoma].

作者信息

Yabuki Hiroshi, Tabata Toshiharu, Sugawara Takafumi, Miyamoto Akira, Fukaya Ken, Saito Tsutomu, Fujimura Shigefumi

机构信息

Department of Thoracic Surgery, Tohoku Pharmaceutical University Hospital, Sendai, Japan.

出版信息

Kyobu Geka. 2013 Dec;66(13):1167-70.

Abstract

The patients was 63-year-old man. He had a chest abnormally shadow pointed out in examination of March, 2012 and referred to our hospital for a close inspection. The chest computed tomography(CT)revealed a mass shadow of 60 mm in left lung. Bronchoscopic examination was done and it was diagnosed as non-small-cell lung cancer by cytology. The clinical stage was cT2bN1M0 and video-assistedthoracic surgery (VATS) left pneumonectomy with mediastinal lymph node dissection was performed. A lot of neoplastic cells which contained melanin in cytoplasm were recognized by pathology and the diagnosis of malignant melanoma was comfirmed. Lymph node metastasis were recognized in #10, #11, #12 and the pathological stage of a disease was pT2bN1M0, pStage IIB. Further examination to find another lesion after surgery was in vain suggesting primary site to be left lung. A adjuvant chemotherapy has not been done. Surgical resection of primary pulmonary malignant melanoma is reported with reference to literatures.

摘要

患者为一名63岁男性。2012年3月检查时发现胸部有异常阴影,遂转诊至我院进行详细检查。胸部计算机断层扫描(CT)显示左肺有一个60毫米的肿块阴影。进行了支气管镜检查,通过细胞学诊断为非小细胞肺癌。临床分期为cT2bN1M0,遂行电视辅助胸腔镜手术(VATS)左肺切除术并进行纵隔淋巴结清扫。病理检查发现许多细胞质中含有黑色素的肿瘤细胞,确诊为恶性黑色素瘤。在第10、11、12组发现淋巴结转移,疾病的病理分期为pT2bN1M0,pIIB期。术后进一步检查未发现其他病变,提示原发部位为左肺。未进行辅助化疗。参考文献报道了原发性肺恶性黑色素瘤的手术切除情况。

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