一名10岁儿童的胫骨潘顿-瓦伦丁杀白细胞素阳性金黄色葡萄球菌骨髓炎。

Panton-Valentine leukocidin-positive Staphylococcus aureus osteomyelitis of the tibia in a 10-year-old child.

作者信息

Elledge Ross O C, Dasari Kishore K, Roy Siten

机构信息

Department of Trauma and Orthopaedic Surgery, Sandwell General Hospital, West Bromwich, UK.

出版信息

J Pediatr Orthop B. 2014 Jul;23(4):358-63. doi: 10.1097/BPB.0000000000000021.

DOI:10.1097/BPB.0000000000000021

PMID:24322533

Abstract

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is increasing in prevalence among asymptomatic carriers and in cases of paediatric soft-tissue infections alike. CA-MRSA may express virulence factors such as Panton-Valentine leukocidin, which makes soft-tissue and hard-tissue infections due to such organisms challenging to treat. We report a case of osteomyelitis of the proximal tibia in a 10-year-old boy and discuss its management in what is to the authors' knowledge the first case report of Panton-Valentine leukocidin-positive CA-MRSA osteomyelitis in a child in the UK.

摘要

社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）在无症状携带者以及小儿软组织感染病例中的患病率均在上升。CA-MRSA可能表达诸如杀白细胞素等毒力因子，这使得由此类病菌引起的软组织和硬组织感染难以治疗。我们报告了一名10岁男孩胫骨近端骨髓炎的病例，并讨论了其治疗方法。据作者所知，这是英国首例关于儿童杀白细胞素阳性CA-MRSA骨髓炎的病例报告。