成人胫骨的杀白细胞素金黄色葡萄球菌骨髓炎——一例报告
Panton-Valentine leukocidin Staphylococcus aureus osteomyelitis of the adult tibia--a case report.
作者信息
Hall M J, Steer J A, Keenan J
机构信息
Derriford Hospital, Plymouth, UK.
出版信息
Ann R Coll Surg Engl. 2010 Mar;92(2):W17-9. doi: 10.1308/147870810X476719.
Panton-Valentine leukocidin toxin producing Staphylococcus aureus (PVLSA) is known to be responsible for recurrent soft tissue infections and more serious invasive infections including necrotising pneumonia, pyomyositis, and osteomyelitis. Most reported cases involving musculoskeletal infection in adults are associated with methicillin-resistant S. aureus (MRSA) PVL-producing strains. We present the case of an adult male with PVL toxin-producing methicillin-sensitive S. aureus (MSSA) osteomyelitis of the tibia which has not previously been described in adults and highlight issues of recognition, treatment, and surgical management of PVLSA osteomyelitis.
已知产生杀白细胞素毒素的金黄色葡萄球菌（PVLSA）会导致复发性软组织感染以及更严重的侵袭性感染，包括坏死性肺炎、脓性肌炎和骨髓炎。大多数报道的涉及成人肌肉骨骼感染的病例与产PVL的耐甲氧西林金黄色葡萄球菌（MRSA）菌株有关。我们报告了一例成年男性胫骨产PVL毒素的甲氧西林敏感金黄色葡萄球菌（MSSA）骨髓炎病例，此前在成人中尚未有过描述，并强调了PVLSA骨髓炎的识别、治疗和外科处理问题。
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