Department of Orthopaedic Surgery, West China Hospital of Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Int Orthop. 2014 Apr;38(4):753-9. doi: 10.1007/s00264-013-2171-3. Epub 2013 Dec 10.
The treatment of elderly KBD knee remains a significant clinical challenge, and clinical data are lacking. This study aimed to prospectively determine the functional outcomes of total knee arthroplasty (TKA) in adult patients with severe Kashin-Beck disease (KBD) of the knee.
Fifteen cases that included 18 occurrences of KBD of the knee were treated by primary knee arthroplasty and followed up for at least two years. Clinical assessments for each patient were performed at time zero (pre-operatively), one, three, six and 12 months and yearly thereafter. The efficacy measures included the visual analogue scale (VAS) pain score, Hospital for Special Surgery (HSS) score, and Functional Score for Adult Tibetans with Kashin-Beck Disease (FSAT-KBD) as well as radiographic findings.
All patients were followed for a mean length of 32.47±10.05 months. All force lines in the lower limbs had been improved significantly. No radiographic evidence of loosening or changes in component positioning was observed at the last follow up. The VAS decreased significantly during the first six months after surgery and was maintained until the last follow up (p < 0.01). Similar trends were found in both HSS and FSAT-KBD, which increased significantly post-operatively (p < 0.01).
Knee arthroplasty can reduce pain and improve function in patients with severe KBD of the knee. Additional studies will be necessary to confirm our findings.
老年 KBD 膝关节的治疗仍然是一个重大的临床挑战,且临床数据有限。本研究旨在前瞻性评估全膝关节置换术(TKA)治疗成人严重膝关节 KBD 的功能结果。
15 例(18 个膝关节)患者接受初次膝关节置换术治疗,至少随访 2 年。对每位患者在时间零(术前)、1 个月、3 个月、6 个月和 12 个月以及此后每年进行临床评估。疗效评估包括视觉模拟评分(VAS)疼痛评分、特种外科医院(HSS)评分、成人西藏 KBD 功能评分(FSAT-KBD)以及影像学发现。
所有患者平均随访 32.47±10.05 个月。所有下肢力线均得到显著改善。末次随访时,未观察到任何松动或部件位置改变的影像学证据。术后前 6 个月 VAS 显著下降,直至末次随访(p<0.01)。HSS 和 FSAT-KBD 也有类似的趋势,术后显著增加(p<0.01)。
膝关节置换术可减轻严重膝关节 KBD 患者的疼痛,改善其功能。需要进一步的研究来证实我们的发现。