Giles Kagmeni, Ernest Moukouri, Christelle Domngang, Georges Nguefack-Tsague, Raoul Cheuteu, Come Ebana Mvogo, Wiedemann Peter
University Teaching Hospital Yaounde (UTHY), Cameroon. ; University of Yaoundé I, Faculty of Medicine and Biomedical Sciences, Cameroon.
Ophthalmol Eye Dis. 2013 Dec 1;5:17-22. doi: 10.4137/OED.S12672. eCollection 2013.
We assessed the outcomes of the use of anterior chamber foldable lens for unilateral aphakia correction at the University Teaching Hospital of Yaounde. In this retrospective, non-comparative, consecutive case series study, we reviewed the records of patients who underwent an operation for aphakia correction by the means of injection of an angular supported foldable lens between January 2009 and December 2011 in the University Teaching Hospital Yaounde. Student's paired t-test was carried out to compare pre-operative and post-operative visual acuity (VA) and intraocular pressure (IOP). P-values less than 0.05 were considered statistically significant. Twenty-one patients were included in the study; twelve were male (57.1%) and nine were female (42.9%). The mean age was 55.38 ± 17.67 years (range 9-75 years). The mean follow-up duration was 5.95 ± 3.14 months (range 2-12 months). The mean log-MAR visual acuity was 1.26 ± 0.46 pre-operatively and 0.78 ± 0.57 post-operatively (P = 0.003). The change in intraocular pressure was not statistically significant. Complications included intraocular hypertension (over 21 mmHg) in 3 patients (14.3%) and macular edema, pupillar ovalization, and retinal detachment in one patient each. The results indicate that injection of an angular support foldable lens in the anterior chamber is a useful technique for the correction of aphakia in eyes without capsular support. More extended follow-up, however, and a larger series of patients are needed to ascertain the effectiveness and safety of this procedure.
我们在雅温得大学教学医院评估了使用前房折叠式人工晶状体矫正单眼无晶状体眼的效果。在这项回顾性、非对照、连续病例系列研究中,我们查阅了2009年1月至2011年12月期间在雅温得大学教学医院接受角支撑折叠式人工晶状体注射矫正无晶状体眼手术的患者记录。采用学生配对t检验比较术前和术后视力(VA)及眼压(IOP)。P值小于0.05被认为具有统计学意义。21例患者纳入研究;12例为男性(57.1%),9例为女性(42.9%)。平均年龄为55.38±17.67岁(范围9 - 75岁)。平均随访时间为5.95±3.14个月(范围2 - 12个月)。术前平均log - MAR视力为1.26±0.46,术后为0.78±0.57(P = 0.003)。眼压变化无统计学意义。并发症包括3例患者(14.3%)发生高眼压(超过21 mmHg),1例患者出现黄斑水肿、瞳孔椭圆形化和视网膜脱离。结果表明,在前房注射角支撑折叠式人工晶状体是矫正无囊膜支撑眼无晶状体眼的一种有用技术。然而,需要更长时间的随访和更大样本量的患者来确定该手术的有效性和安全性。