良性细胞对：乳腺病变穿刺细胞学涂片检查中的一个重要实体。
Benign pairs: a significant entity in aspiration cytology smears from breast lesions.
作者信息
Rathi Monika, Kala Pooja, Gupta Atul, Budania Satish Kumar, Ahuja Harshkiran
机构信息
Teerthanker Mahaveer Medical College and Research Centre, Moradabad, India. ; Department of Pathology, Sarojini Naidu Medical College, Agra, India.
出版信息
Clin Med Insights Pathol. 2013 Nov 28;6:13-6. doi: 10.4137/CPath.S13273. eCollection 2013.
INTRODUCTION
Fine needle aspiration cytology (FNAC) is a reliable diagnostic tool used to diagnose breast lesions preoperatively. However, FNAC is also associated with diagnostic pitfalls. Further studies are needed to improve its diagnostic efficacy. We noticed ovoid, bare nuclei arranged in closely touching diads (benign pairs) in a significant number of cytology smears. This prompted us to assess their diagnostic utility.
MATERIALS AND METHODS
This was a prospective study conducted in Sarojini NaiduMedical College, Agra, India. Quantitative estimation of benign pairs per 1000 ductal cells in at least 20 high power field was attempted in cytology smears of 128 cases.
RESULTS
The average number of pairs in benign and malignant lesions was calculated as 7.07 + 5.96 and 0.28 + 0.78, respectively. Statistical analysis showed a significant difference between the number of pairs in benign and malignant cases (P < 0.0005).
CONCLUSIONS
Quantitative estimation of benign pairs is helpful in distinguishing benign from malignant cases.
引言
细针穿刺细胞学检查（FNAC）是一种用于术前诊断乳腺病变的可靠诊断工具。然而，FNAC也存在诊断陷阱。需要进一步研究以提高其诊断效能。我们在大量细胞学涂片上注意到卵形、裸核紧密相连成对排列（良性配对）。这促使我们评估它们的诊断效用。
材料与方法
这是一项在印度阿格拉的萨罗吉尼·奈杜医学院进行的前瞻性研究。试图在128例病例的细胞学涂片中，在至少20个高倍视野下对每1000个导管细胞中的良性配对进行定量评估。
结果
良性和恶性病变中配对的平均数量分别计算为7.07 + 5.96和0.28 + 0.78。统计分析显示良性和恶性病例中配对数量存在显著差异（P < 0.0005）。
结论
良性配对的定量评估有助于区分良性和恶性病例。
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