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肺转移瘤手术治疗的远期结果

Late results of surgical treatment of pulmonary metastases.

作者信息

Vogt-Moykopf I, Meyer G, Merkle N M, Bülzebruck H, Langsdorf M

出版信息

Thorac Cardiovasc Surg. 1986 Nov;34 Spec No 2:143-8. doi: 10.1055/s-2007-1022193.

Abstract

Surgical removal of one or several metastases with a potentially curative aim is possible in the case of isolated pulmonary metastases. The surgery is always part of an overall oncological concept. Between 1972 and 1984, surgery was indicated in 295 cases in 261 patients and 304 thoracotomies were performed. The procedure was classified as potentially curative in 76% of the cases. The 5-year survival probability in this patient group amounted to 38% for all organic tumors. The definitely best prognosis with 5-year survival rates of 42% is observed for caval metastatic carcinoma. Due to the excellent chemotherapeutical regimens, testicular teratomas reach the best individual result with a 3-year survival probability of 71%. Decisive for the long-term prognosis is the removal of all visible and palpable metastases. If radical resectability is possible, the number of metastases is only of secondary importance. Besides radicality, metastatic route and type of the primary tumor, duration of the disease-free interval and the size of the metastases are also of prognostic significance. Predominating resection procedures are the atypical and segment resection and the enucleation which yield the best survival rates.

摘要

对于孤立性肺转移瘤,以潜在治愈为目的手术切除一个或多个转移灶是可行的。该手术始终是整体肿瘤治疗理念的一部分。1972年至1984年间,261例患者中的295例接受了手术治疗,共进行了304次开胸手术。76%的病例手术被归类为潜在可治愈。所有实体肿瘤患者组的5年生存率为38%。腔静脉转移癌的5年生存率为42%,预后绝对最佳。由于化疗方案出色,睾丸畸胎瘤个体预后最佳,3年生存率为71%。决定长期预后的是切除所有可见和可触及的转移灶。如果有可能进行根治性切除,转移灶数量仅为次要因素。除了根治性、转移途径和原发肿瘤类型外,无病间期的长短和转移灶大小也具有预后意义。主要的切除方法是非典型和节段性切除以及摘除术,这些方法生存率最佳。

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