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年轻患者风湿性主动脉瓣疾病的修复选择:心包瓣叶延长的潜在问题。

Repair options in rheumatic aortic valve disease in young patients: potential problems with pericardial cusp extension.

作者信息

d'Udekem Yves, Sharma Varun

机构信息

Department of Cardiac Surgery, Royal Children's Hospital, Melbourne, Australia.

出版信息

World J Pediatr Congenit Heart Surg. 2013 Oct;4(4):392-6. doi: 10.1177/2150135113496440.

DOI:10.1177/2150135113496440
PMID:24327633
Abstract

This article outlines the arguments against cusp extension, which were put forward at the debate entitled "Repair options in rheumatic aortic disease in young patients" at the Symposium on Surgery for Rheumatic Heart Disease organized by The World Society for Pediatric and Congenital Heart Surgery at The Sixth World Congress of Paediatric Cardiology and Cardiac Surgery, February 17-22, 2013, Cape Town, South Africa. We propose that cusp extension should be avoided because (1) these patients are usually old enough to receive the same valve substitutes as adults, (2) lack of antibioprophylaxis compliance will likely result in early reintervention, (3) cusp extension mandates rerepair within four to five years and is more expensive in the long term, and (4) it is fraught with myocardial ischemic complications. Thus, a mechanical, bioprosthetic, or autograft valve replacement may be superior for patients unless they have unrestricted access to repetitive interventions. A single surgical technique does not suffice in the treatment of rheumatic aortic valve disease, and a diversified approach should be adopted dependent on both the patients' characteristics and the financial constraints.

摘要

本文概述了反对瓣叶延长术的观点,这些观点是在2013年2月17日至22日于南非开普敦举行的第六届世界儿科心脏病学和心脏外科学大会上,由世界小儿和先天性心脏外科学会组织的风湿性心脏病外科研讨会上,在题为“年轻患者风湿性主动脉疾病的修复选择”的辩论中提出的。我们建议应避免进行瓣叶延长术,原因如下:(1)这些患者通常年龄足够大,可以接受与成人相同的瓣膜替代物;(2)缺乏抗生素预防依从性可能会导致早期再次干预;(3)瓣叶延长术要求在四到五年内再次修复,从长期来看成本更高;(4)该手术充满心肌缺血并发症。因此,对于患者而言,除非他们能够不受限制地接受重复干预,否则机械瓣膜、生物瓣膜或自体瓣膜置换术可能更具优势。单一的手术技术不足以治疗风湿性主动脉瓣疾病,应根据患者的特征和经济限制采取多样化的方法。

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