Kang Hyo Jae, Park Young Sik, Lee Chang-Hoon, Lee Sang-Min, Yim Jae-Joon, Yoo Chul-Gyu, Kim Young Whan, Han Sung Koo, Chai Jong-Yil, Lee Jinwoo
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine, Seoul 110-744, Korea.
Korean J Parasitol. 2013 Oct;51(5):569-72. doi: 10.3347/kjp.2013.51.5.569. Epub 2013 Oct 31.
Dirofilariasis is a rare disease in humans. We report here a case of a 48-year-old male who was diagnosed with pulmonary dirofilariasis in Korea. On chest radiographs, a coin lesion of 1 cm in diameter was shown. Although it looked like a benign inflammatory nodule, malignancy could not be excluded. So, the nodule was resected by video-assisted thoracic surgery. Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. In the center of the necrotic nodules, a degenerating parasitic organism was found. The parasite had prominent internal cuticular ridges and thick cuticle, a well-developed muscle layer, an intestinal tube, and uterine tubules. The parasite was diagnosed as an immature female worm of Dirofilaria immitis. This is the second reported case of human pulmonary dirofilariasis in Korea.
丝虫病在人类中是一种罕见疾病。我们在此报告一例48岁男性在韩国被诊断为肺丝虫病的病例。胸部X光片显示一个直径1厘米的硬币状病灶。尽管它看起来像一个良性炎性结节，但不能排除恶性肿瘤的可能。因此，通过电视辅助胸腔镜手术切除了该结节。病理检查可见由凝固性坏死伴纤维组织和肉芽组织边缘组成的慢性肉芽肿性炎症。在坏死结节的中心发现了一个正在退化的寄生生物。该寄生虫有明显的内部角质嵴和厚角质层、发育良好的肌肉层、肠管和子宫小管。该寄生虫被诊断为未成熟的犬恶丝虫雌虫。这是韩国第二例报告的人类肺丝虫病病例。
