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新型合成色胺5-甲氧基-DALT中毒所致谵妄

Delirium due to intoxication from the novel synthetic tryptamine 5-MeO-DALT.

作者信息

Jovel Andres, Felthous Alan, Bhattacharyya Anjan

机构信息

Department of Neurology and Psychiatry, Saint Louis University School of Medicine, 1438 South Grand Boulevard, St. Louis, MO, 63104.

出版信息

J Forensic Sci. 2014 May;59(3):844-6. doi: 10.1111/1556-4029.12367. Epub 2013 Dec 13.

DOI:10.1111/1556-4029.12367
PMID:24329118
Abstract

Synthetic tryptamines have gained popularity for their hallucinogenic properties, unscheduled status, and availability from "head shops" and through the internet. Here, we present a case of synthetic tryptamine-induced delirium secondary to 5-MeO-DALT ingestion in a previously healthy young male. 5-MeO-DALT led to the hospitalization of our patient after ingestion of a standard dose, presenting with extreme agitation, tachycardia, diaphoresis, and combativeness leading to physical restraint and intravenous sedation. A search of PubMed, Ovid, and Google Scholar for keywords of "5-MeO-DALT," "5-methoxy-N,N-diallyltryptamine," or "Lucy-N-Nate" found no case reports or clinical articles in the literature. Rapid emergence and commercialization of this novel synthetic tryptamine 5-MeO-DALT points to the importance of health care and forensic professionals keeping abreast of the latest drugs of abuse and their clinical features. The authors hope this report leads the way in disseminating the potential risks associated with unscheduled and unregulated substances, synthetic tryptamines such as 5-MeO-DALT in particular.

摘要

合成色胺因其致幻特性、未被列入管制药品名单的状态以及可从“烟具店”和通过互联网获取而受到欢迎。在此,我们报告一例在一名既往健康的年轻男性中,因摄入5-甲氧基-N,N-二烯丙基色胺(5-MeO-DALT)继发合成色胺所致谵妄的病例。摄入标准剂量的5-MeO-DALT后,我们的患者被收治入院,表现为极度烦躁、心动过速、出汗以及具有攻击性,导致需要身体约束和静脉镇静。在PubMed、Ovid和谷歌学术中搜索“5-MeO-DALT”“5-甲氧基-N,N-二烯丙基色胺”或“露西-N-奈特”等关键词,未在文献中发现病例报告或临床文章。这种新型合成色胺5-MeO-DALT的迅速出现和商业化表明,医护人员和法医专业人员了解最新滥用药物及其临床特征非常重要。作者希望本报告能引领传播与未列入管制和不受监管物质相关的潜在风险,特别是像5-MeO-DALT这样的合成色胺。

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