Pohanka M
Bratisl Lek Listy. 2013;114(12):726-34. doi: 10.4149/bll_2013_153.
Butyrylcholinesterase (BChE) is an enzyme expressed in multiple organs and abundant in plasma. BChE can fluctuate in course of several reasons while both hypercholiensterasemia and hypocholinesterasemia are known. Considering evidence of BChE activity alterations, hepatocellular carcinoma, chronic liver diseases and poisoning with carbamates or organophosphates can be diagnosed by activity assay. BChE is responsible for detoxification reactions, and the compounds such as cocaine, succinylcholine, and acetylsalicylic acid are degraded in the body. The detoxification can be slowed in patients carrying the K variant of the enzyme. Summarization of literature, discussion on the meaning of BChE in the body, and the principles of BChE assay in samples are described in the review (Tab. 2, Fig. 8, Ref. 86). Text in PDF www.elis.sk.
丁酰胆碱酯酶（BChE）是一种在多个器官中表达且在血浆中含量丰富的酶。BChE会因多种原因而波动，高胆碱酯酶血症和低胆碱酯酶血症均已为人所知。鉴于BChE活性改变的证据，可通过活性测定来诊断肝细胞癌、慢性肝病以及氨基甲酸酯类或有机磷酸酯类中毒。BChE负责解毒反应，可卡因、琥珀酰胆碱和乙酰水杨酸等化合物在体内会被降解。携带该酶K变体的患者解毒过程可能会减慢。该综述描述了文献总结、对BChE在体内意义的讨论以及样品中BChE测定的原理（表2、图8、参考文献86）。文本来源于www.elis.sk的PDF文档。
