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[用于检测老年斑和细胞内神经原纤维的 Bielschowsky 方法的改良]

[Modification of Bielschowsky's method for detecting senile plaques and intracellular neurofibrils].

作者信息

Antonova A M

出版信息

Biull Eksp Biol Med. 1987 Jan;103(1):117-9.

PMID:2432964
Abstract

The distinction of the modification of Bielschowsky's method lies in additional colouring of silver-golden sections with strong solutions of stable cresyl-violet and acetic acid, as well as in recommendations to use precise-profile cortical sections. The given modification helps to obtain preparations with definite orientation and guaranteed identification of different nerve tissue elements. The preparations obtained can be employed for quantitative analysis and for a detailed study of thin specific structures and cytologic properties of pathologically changed nerve and glial cells.

摘要

比尔绍夫斯基方法的改进之处在于,用浓的稳定甲酚紫和乙酸溶液对银金切片进行额外染色,以及建议使用精确轮廓的皮质切片。这种改进有助于获得具有明确方向且能保证识别不同神经组织成分的标本。所获得的标本可用于定量分析,以及对病理改变的神经和胶质细胞的精细特定结构和细胞学特性进行详细研究。

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