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减轻中耳炎疾病负担面临的挑战:耳鼻喉科医生对改善治疗及预防前景的看法

Challenges in reducing the burden of otitis media disease: an ENT perspective on improving management and prospects for prevention.

作者信息

Grevers Gerhard

机构信息

ENT-Center, Prinzenweg 1, 82319 Starnberg, Germany.

出版信息

Int J Pediatr Otorhinolaryngol. 2010 Jun;74(6):572-7. doi: 10.1016/j.ijporl.2010.03.049. Epub 2010 Apr 20.

Abstract

Acute otitis media (AOM) is a major public health concern. This frequent disease of childhood is a leading cause of physician visits, a major component of paediatric healthcare burden, and a key contributor to antibiotic resistance. An international expert group comprising mainly ear, nose, and throat physicians met in June 2008 to discuss the optimal management of AOM, particularly with regards to unmet needs in diagnosis and management. Current guidelines do not help identify which patients are most at risk for severe or complicated AOM. Diagnosis of AOM is also complicated by a lack of correlation between clinical signs and symptoms and responsible pathogens. Consequently, treatment of AOM is not always appropriate, and the long-term overuse of antibiotics in AOM reduces the effectiveness of treatment and places children at risk for drug-resistant infections. There is a need for educational and research initiatives to improve diagnostic accuracy and management of AOM. Because there is currently no ideal treatment, vaccination is an attractive additional approach for managing AOM and reducing its burden.

摘要

急性中耳炎(AOM)是一个重大的公共卫生问题。这种常见的儿童疾病是导致就医的主要原因、儿科医疗负担的主要组成部分,也是抗生素耐药性的关键促成因素。一个主要由耳鼻喉科医生组成的国际专家小组于2008年6月开会讨论AOM的最佳管理方法,特别是在诊断和管理方面未满足的需求。当前的指南无助于确定哪些患者最易患严重或复杂的AOM。AOM的诊断也因临床体征和症状与致病病原体之间缺乏相关性而变得复杂。因此,AOM的治疗并不总是恰当的,AOM中长期过度使用抗生素会降低治疗效果,并使儿童面临耐药性感染的风险。需要开展教育和研究举措来提高AOM的诊断准确性和管理水平。由于目前尚无理想的治疗方法,接种疫苗是管理AOM并减轻其负担的一种有吸引力的额外方法。

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