Bøås H, Tapia G, Rasmussen T, Rønningen K S
Norwegian Institute of Public Health,Division of Epidemiology, Oslo,Norway.
Norwegian Institute of Public Health,Division of Institute Resources, Oslo,Norway.
Epidemiol Infect. 2014 Oct;142(10):2114-20. doi: 10.1017/S0950268813003154. Epub 2013 Dec 13.
Studies investigating the association between Enterobius vermicularis and allergic conditions have shown conflicting results. This study was conducted to test for any such associations in Norwegian children. Parents were asked to answer questionnaires concerning their children's history of allergies, wheezing or eczema and pinworm infections. Current pinworm infections were diagnosed by microscopic examination of anal scotch tape samples. The data were analysed using logistic regression. Atopic eczema, allergy or wheezing was reported to be confirmed by a physician in 23% of the children (84/364). A possible association between current pinworm infections and food allergy was found, with 17·5% of children without food allergy testing positive for pinworms, compared to 36·8% of children with food allergy (odds ratio 2·9, 95% confidence interval 1·1-8·0). No association was found between past pinworm treatments and present atopic conditions. The association between current E. vermicularis infections and food allergy warrants further study.
关于蠕形住肠线虫与过敏状况之间关联的研究结果相互矛盾。本研究旨在检测挪威儿童中是否存在此类关联。研究要求家长回答有关其子女过敏史、喘息或湿疹以及蛲虫感染情况的问卷。通过对肛门透明胶带样本进行显微镜检查来诊断当前的蛲虫感染。使用逻辑回归分析数据。23%的儿童（84/364）经医生确诊患有特应性皮炎、过敏或喘息。研究发现当前的蛲虫感染与食物过敏之间可能存在关联，17.5%未进行食物过敏检测的儿童蛲虫检测呈阳性，相比之下，患有食物过敏的儿童这一比例为36.8%（比值比2.9，95%置信区间1.1 - 8.0）。未发现既往蛲虫治疗与当前特应性状况之间存在关联。当前蠕形住肠线虫感染与食物过敏之间的关联值得进一步研究。
