Liu Xiu-rong, Li Jun-juan, Wang Li-ye, Wang Yan, Chen Wei-hong, Zheng Xiu-hui, Li Le-le, Hao Fu-rong, Wu Shou-ling
Affiliated Kailuan General Hospital.
Graduate School, Hebei Union University, Tangshan 063000, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Sep;34(9):884-7.
To explore the relationship between the level of waist circumference (WC) and the impaired fasting glucose (IFG) in people working for the Kailuan Enterprise.
A total of 101 510 subjects from the employees of Kailuan Group who took part in the health examination between 2006 to 2007, with fasting plasma glucose (FPG) < 6.1 mmol/L, no history of diabetes, completed data on FPG and WC examination and without using hypoglycemic agents, were selected as the observation cohort. Subjects who did not participate in the health examination from 2010 to 2011 and had incomplete data were finally excluded, ended up with 52 099 subjects available for final analysis. According to the baseline WC measurements and its quartile in the health examinations during 2006 to 2007, people under observation were divided into four groups (first, second, third and the forth quartile groups). Multiple logistic regression analysis was used to test the relation between the increasing of WC and IFG.
(1) The incidence rate of IFG in the obese group was higher than that in non-obese group (10.5% vs. 6.8% , P < 0.01), along with an increasing WC noticed in the 4 quartile groups and the incidence rates of IFG were progressively increased, being 6.0%, 7.1%, 8.6% and 11.0% respectively in the total population(7.0%, 7.9%, 9.1% and 11.4% in males, 2.5%, 4.6%, 6.8% and 9.8% in females). (2)Results from the multiple logistic regression analysis showed that, when compared with the first quartile group, the second, third and fourth quartile groups had increased risks of IFG after adjustment on age, gender and other risk factors in the total population, with the OR values being 1.03, 1.15 and 1.30 respectively. After adjusting the above factors in genders, we also noticed the increased risks of IFG, with the OR value being 1.45, 1.66 and 2.08 in males, while 1.00, 1.09 and 1.23 in females, respectively. The influence of the second and third quartile groups on IFG was not significant in females, however.
The incidence of IFG showed an increasing trend with the increase of WC.
探讨开滦企业职工腰围水平与空腹血糖受损（IFG）之间的关系。
选取2006年至2007年参加健康体检的开滦集团职工中，空腹血糖（FPG）<6.1 mmol/L、无糖尿病史、完成FPG和腰围检查数据且未使用降糖药物的101510名受试者作为观察队列。最终排除2010年至2011年未参加健康体检及数据不完整的受试者，得到52099名可供最终分析的受试者。根据2006年至2007年健康体检时的基线腰围测量值及其四分位数，将观察对象分为四组（第一、第二、第三和第四四分位数组）。采用多因素logistic回归分析检验腰围增加与IFG之间的关系。
（1）肥胖组IFG发病率高于非肥胖组（10.5%对6.8%，P<0.01），随着四分位数组腰围的增加，IFG发病率逐渐升高，总体人群中分别为6.0%、7.1%、8.6%和11.0%（男性分别为7.0%、7.9%、9.1%和11.4%，女性分别为2.5%、4.6%、6.8%和9.8%）。（2）多因素logistic回归分析结果显示：在总体人群中，与第一四分位数组相比，调整年龄、性别等危险因素后，第二、第三和第四四分位数组IFG风险增加，OR值分别为1.03、1.15和1.30。在性别中调整上述因素后，也观察到IFG风险增加，男性OR值分别为1.45、1.66和2.08，女性分别为1.00、1.09和1.23。然而，第二和第三四分位数组对女性IFG的影响不显著。
IFG发病率随腰围增加呈上升趋势。
