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统一肝素方案实施前后的围产期血栓预防

Peripartum thromboprophylaxis before and after implementation of a uniform heparin protocol.

作者信息

Anderson Sarah B, Lin Stephanie N, Reiss Jonathan, Skupski Daniel, Grunebaum Amos

出版信息

J Perinat Med. 2014 Mar;42(2):219-23. doi: 10.1515/jpm-2013-0165.

Abstract

AIM

The objective of this study was to assess the utilization of postpartum thromboprophylaxis with heparin in patients according to the Royal College of Obstetrics and Gynaecology Green-Top guidelines after change from an opt-in to an opt-out policy for health care providers ordering heparin thromboprophylaxis after cesarean delivery.

STUDY DESIGN

The present study is a retrospective review of 500 consecutive births at one academic institution before and after implementation of a uniform thromboprophylaxis policy with heparin for all cesarean deliveries. An "opt-out" policy for ordering physicians was implemented by automatically defaulting to order heparin in the electronic order set used after cesarean delivery.

RESULTS

Cesarean delivery rates were similar during both time periods. Heparin thromboprophylaxis was indicated in 99.6% of the cesarean delivery population before implementation and 94.5% after implementation. Prior to implementation only 5.7% received thromboprophylaxis compared to 96.1% after implementation, P<0.0001.

CONCLUSION

An opt-out heparin thromboprophylaxis policy improves compliance with thromboprophylaxis guidelines compared to an opt-in policy. Institutions should consider opt-out heparin thromboprophylaxis policies after cesarean deliveries to improve compliance with recommendations.

摘要

目的

本研究的目的是根据皇家妇产科学院的绿色指南,评估在剖宫产术后医疗保健提供者从选择加入改为选择退出肝素预防血栓形成政策后,患者产后肝素预防血栓形成的使用情况。

研究设计

本研究是对一家学术机构500例连续剖宫产分娩前后实施统一肝素预防血栓形成政策的回顾性研究。通过在剖宫产术后使用的电子医嘱集中自动默认开具肝素,对开具医嘱的医生实施“选择退出”政策。

结果

两个时间段的剖宫产率相似。实施前99.6%的剖宫产人群需要肝素预防血栓形成,实施后为94.5%。实施前只有5.7%的患者接受了预防血栓形成治疗,实施后为96.1%,P<0.0001。

结论

与选择加入政策相比,选择退出肝素预防血栓形成政策可提高对预防血栓形成指南的依从性。各机构应考虑在剖宫产术后采用选择退出肝素预防血栓形成政策,以提高对建议的依从性。

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