Murphy M N, Lorimer S M, Glennon P E
J Surg Oncol. 1987 Jan;34(1):68-72. doi: 10.1002/jso.2930340117.
A single case of symptomatic metastatic melanoma to the gallbladder, with roentgenographic findings of gallbladder disease, is presented. Review of the 12 previously reported cases of symptomatic metastatic biliary melanoma and of those reports of "primary" melanoma of the gallbladder reveals marked similarity between the two groups, with regard to relative size, pathologic description, number, and location of lesions. This, together with the finding of "junctional activity" in our case, leads us to believe that most if not all melanomas present in the gallbladder are metastatic deposits from a known, undetected, or regressed primary locus elsewhere. Surgical removal, even in the presence of disseminated disease, is a worthwhile palliative procedure.
本文报告了一例有症状的胆囊转移性黑色素瘤，伴有胆囊疾病的X线表现。回顾之前报道的12例有症状的转移性胆管黑色素瘤病例以及那些“原发性”胆囊黑色素瘤的报告发现，两组在病变的相对大小、病理描述、数量和位置方面有显著相似性。这一点，再加上我们病例中发现的“交界活性”，使我们相信，胆囊中出现的大多数（如果不是全部）黑色素瘤是来自其他部位已知、未被发现或已消退的原发性病灶的转移灶。即使存在播散性疾病，手术切除仍是一种值得的姑息性治疗方法。
