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Some effects of oestrogens on [3H]-mepyramine binding in rat brain.

作者信息

Anuka J A, Thomas P J, Walker J

出版信息

Methods Find Exp Clin Pharmacol. 1986 Nov;8(11):655-60.

PMID:2433554
Abstract

Oestrogen depress [3H]-mepyramine binding in the amygdala, hypothalamus and cerebral cortex of rats. These effects of oestrogens are prevented by concurrent administration of inhibitors of cyclic 3'5' AMP phosphodiesterase, suggesting that the hormones act by reducing the activity of adenylate cyclase.

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