Dipartmento di Scienze Radiologiche, Oncologiche ed Anatomo-patologiche, Policlinico Umberto I, Università di Roma "Sapienza", Viale Regina Elena 324, 00161, Rome, Italy,
Radiol Med. 2014 May;119(5):309-17. doi: 10.1007/s11547-013-0341-4. Epub 2013 Dec 12.
The aim of this work was to compare the prevalence of right ventricle involvement in a population of patients with myocardial infarction as detected by cardiac magnetic resonance (CMR), clinical presentation, electrocardiographic (ECG) and echocardiographic criteria.
A total of 97 consecutive patients, admitted to our institution for acute myocardial infarction, underwent a standard CMR examination within 5 days after the event. The presence of myocardial oedema and late enhancement of the right ventricle were compared to infarct location (anterior vs. inferior), clinical data, ECG, echocardiography results and other CMR findings. The results were analysed statistically using the Student's t test for independent samples and the K statistic.
Among the 97 patients included in the study, a diagnosis of right ventricular infarction was established in 12, 14 and 24 cases on the basis of the clinical data, the ECG and echocardiography, respectively. CMR demonstrated myocardial oedema and late enhancement of the right ventricle in 48 and 32 cases, respectively. The right ventricle was involved in 46 % of patients with inferior myocardial infarction (15/32) and in 30 % with anterior myocardial infarction (17/56), correlating to a worsening of both right and left ventricular performance (p = 0.001-0.05).
The right ventricle is frequently involved in myocardial infarction, correlating to a worse functional impairment of both ventricles and a worse prognosis. This finding, which is often underestimated by traditional cardiological tests, is well revealed by CMR, with potential clinical and therapeutic impact.
本研究旨在比较心脏磁共振(CMR)检测到的心肌梗死后右心室受累的发生率,并与临床表现、心电图(ECG)和超声心动图标准进行比较。
共纳入 97 例连续急性心肌梗死患者,于发病后 5 天内行标准 CMR 检查。比较心肌水肿和右心室晚期增强的存在与梗死部位(前壁 vs. 下壁)、临床数据、心电图、超声心动图结果和其他 CMR 发现。采用独立样本 Student's t 检验和 K 统计分析结果。
在纳入研究的 97 例患者中,根据临床数据、心电图和超声心动图,分别有 12、14 和 24 例诊断为右心室梗死。CMR 显示右心室心肌水肿和晚期增强分别为 48 例和 32 例。下壁心肌梗死患者中右心室受累占 46%(15/32),前壁心肌梗死患者中右心室受累占 30%(17/56),与右心室和左心室功能均恶化相关(p=0.001-0.05)。
右心室在心肌梗死中经常受累,与双心室功能障碍恶化和预后不良相关。这一发现通常被传统的心脏病学检查低估,而 CMR 则能很好地揭示这一点,具有潜在的临床和治疗意义。