Xia Y, Zhang A Z, Cao X D
Acupunct Electrother Res. 1986;11(3-4):191-8. doi: 10.3727/036012986816359076.
Using specific antisera microinjected into periaqueductal grey (PAG), we further studied the mechanism of the analogous electroacupuncture, deep peroneal nerve stimulation (DPNS), inhibition on the experimental arrhythmia, hypothalamic stimulation-induced ventricular extrasystoles (HVE). Neither normal serum nor anti-leu-enkephalin antiserum interfered with DPNS inhibition; anti-dynorphin A (1-8) tended to attenuate the inhibition; and anti-beta-endorphin antiserum blocked it. The results provided further evidence for the hypothesis that beta-endorphin in PAG plays an important role in the neural circuit of DPNS inhibition on HVE.
通过将特异性抗血清微量注射到中脑导水管周围灰质（PAG）中，我们进一步研究了类似电针、腓深神经刺激（DPNS）对实验性心律失常、下丘脑刺激诱发室性期前收缩（HVE）的抑制机制。正常血清和抗亮氨酸脑啡肽抗血清均不干扰DPNS的抑制作用；抗强啡肽A（1-8）倾向于减弱这种抑制作用；而抗β-内啡肽抗血清则阻断了这种抑制作用。这些结果为以下假说提供了进一步的证据，即PAG中的β-内啡肽在DPNS抑制HVE的神经回路中起重要作用。
