Yanagimoto Hiroaki, Satoi Sohei, Toyokawa Hideyoshi, Yamamoto Tomohisa, Hirooka Satoshi, Yamao Jun, Yamaki So, Ryota Hironori, Matsui Yoichi, Kwon A-Hon
Department of Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan.
J Hepatobiliary Pancreat Sci. 2014 Jul;21(7):473-8. doi: 10.1002/jhbp.59. Epub 2013 Dec 15.
The most common postoperative complication after distal pancreatectomy (DP) is still postoperative pancreatic fistula (POPF), which is closely associated with other major complications and remains an unsolved problem.
This retrospective study included 47 consecutive patients who underwent a distal pancreatectomy with (DP-PG group, n = 21) or without (DP group, n = 26) duct-to-mucosa pancreaticogastrostomy from June 2010 to May 2012. Clinical data including POPF-related complications (POPF, fluid collection, intra-abdominal abscess, bleeding and delayed gastric emptying) as a primary endpoint were compared between the two groups.
The frequencies of POPF-related complications as well as overall POPF and complications in the DP-PG group were lower than in the DP group (P = 0.037, P < 0.001, respectively). The 30 days morbidity after hospital discharge in the DP-PG group was less than in the DP group (P = 0.014). In both groups median hospital stay was similar. Although additional time needed for pancreaticogastrostomy was 35 (20-55) min, there was no difference in operative times. Patients in the DP group had a higher medical cost for hospitalization than the DP-PG group (P = 0.048).
Pancreaticogastrostomy as an additional procedure following distal pancreatectomy was associated with a reduced rate of POPF-related complications that resulted in relatively lower medical cost for hospitalization.
胰体尾切除术(DP)后最常见的术后并发症仍是术后胰瘘(POPF),它与其他主要并发症密切相关,仍是一个未解决的问题。
这项回顾性研究纳入了2010年6月至2012年5月期间连续接受胰体尾切除术的47例患者,其中21例行胰管-黏膜胰胃吻合术(DP-PG组),26例未行该吻合术(DP组)。以POPF相关并发症(POPF、积液、腹腔内脓肿、出血和胃排空延迟)作为主要终点,比较两组的临床资料。
DP-PG组中POPF相关并发症以及总体POPF和并发症的发生率低于DP组(分别为P = 0.037,P < 0.001)。DP-PG组出院后30天的发病率低于DP组(P = 0.014)。两组的中位住院时间相似。虽然胰胃吻合术所需的额外时间为35(20 - 55)分钟,但手术时间无差异。DP组患者的住院医疗费用高于DP-PG组(P = 0.048)。
胰胃吻合术作为胰体尾切除术后的附加手术,与POPF相关并发症发生率降低有关,从而使住院医疗费用相对较低。