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本文引用的文献

1
The 13-year experience of performing pancreaticoduodenectomy in a mid-volume municipal hospital.一家中等规模市级医院开展胰十二指肠切除术的13年经验。
Ann Surg Treat Res. 2017 Feb;92(2):73-81. doi: 10.4174/astr.2017.92.2.73. Epub 2017 Jan 31.
2
The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After.国际研究小组(ISGPS)术后胰瘘定义与分级的2016年更新:11年后
Surgery. 2017 Mar;161(3):584-591. doi: 10.1016/j.surg.2016.11.014. Epub 2016 Dec 28.
3
Clinical Effect of Surgical Volume.手术量的临床效果。
N Engl J Med. 2016 Apr 7;374(14):1380-2. doi: 10.1056/NEJMclde1513948.
4
Pancreatoduodenectomy: Risk Factors of Postoperative Pancreatic Fistula.胰十二指肠切除术:术后胰瘘的危险因素
Hepatogastroenterology. 2014 Jun;61(132):1124-32.
5
Sealing pancreaticojejunostomy in combination with duct parenchyma to mucosa seromuscular one-layer anastomosis: a novel technique to prevent pancreatic fistula after pancreaticoduodenectomy.胰管实质至黏膜浆肌层一层吻合联合封闭胰肠吻合术:一种预防胰十二指肠切除术后胰瘘的新技术
J Am Coll Surg. 2015 May;220(5):e71-7. doi: 10.1016/j.jamcollsurg.2014.12.047. Epub 2015 Jan 15.
6
Pancreaticogastrostomy following distal pancreatectomy prevents pancreatic fistula-related complications.远端胰腺切除术后行胰胃吻合术可预防胰瘘相关并发症。
J Hepatobiliary Pancreat Sci. 2014 Jul;21(7):473-8. doi: 10.1002/jhbp.59. Epub 2013 Dec 15.
7
Evolution of pancreatoduodenectomy in a tertiary cancer center in India: improved results from service reconfiguration.印度一家三级癌症中心的胰十二指肠切除术演变:服务重组带来的更好结果。
Pancreatology. 2013 Jan-Feb;13(1):63-71. doi: 10.1016/j.pan.2012.11.302. Epub 2012 Nov 10.
8
Impact of surgical volume on nationwide hospital mortality after pancreaticoduodenectomy.手术量对胰十二指肠切除术后全国医院死亡率的影响。
World J Gastroenterol. 2012 Aug 21;18(31):4175-81. doi: 10.3748/wjg.v18.i31.4175.
9
Hospital volume and failure to rescue with high-risk surgery.医院手术量与高危手术的抢救失败。
Med Care. 2011 Dec;49(12):1076-81. doi: 10.1097/MLR.0b013e3182329b97.
10
Pancreaticoduodenectomy in a government medical college-should we proceed!!!在一所政府医学院进行胰十二指肠切除术——我们应该继续吗?!!!
Indian J Surg. 2010 Oct;72(5):381-5. doi: 10.1007/s12262-010-0153-x. Epub 2010 Nov 16.

印度二线城市低手术量中心胰十二指肠切除术的结果

Outcome of Pancreaticoduodenectomy at Low-Volume Centre in Tier-II City of India.

作者信息

Vinchurkar Kumar, Pattanshetti Vishwanath M, Togale Manoj, Hazare Santosh, Gokak Varadraj

机构信息

Consultant Surgical Oncology, KLES Dr Prabhakar Kore Hospital & MRC, Belagavi, Karnataka India.

2Department of General Surgery, J N Medical College, KLE University and KLES Dr Prabhakar Kore Hospital & MRC, Belagavi, Karnataka 590010 India.

出版信息

Indian J Surg Oncol. 2018 Jun;9(2):220-224. doi: 10.1007/s13193-018-0744-8. Epub 2018 Apr 6.

DOI:10.1007/s13193-018-0744-8
PMID:29887705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5984862/
Abstract

Currently, pancreaticoduodenectomy (PD) is considered a common and feasibly performed surgery for periampullary tumours, but it is still a high-risk surgical procedure with potential morbidity and mortality rates. Previously, it was emphasised for the need of high-volume centres to perform specialised surgery such as PD. The authors have made an attempt to know the relation between low-volume centre and outcomes of PD. The study was conducted in a Tier-II city referral hospital located in Karnataka, India. A total of 37 patients with suspected periampullary neoplasms underwent surgical exploration with curative intent over a period of 4 years, i.e. from May 2012 to May 2016. Out of 37 patients, 26 underwent PD, either classic Whipple resection ( = 01) or pylorus-preserving modification ( = 25). In 11 patients, resection was not possible, where biliary and gastric drainage procedures were done. All patients were treated by standardised post-operative care protocols for pancreatic resection used at our centre. We recorded the perioperative outcome along with demographics, indications for surgery, and pre- and intra-operative factors of PD. Post-operative pancreatic fistulae were evident in 4 patients. Two patients had hepaticojejunostomy leak. One patient had chyle leak. Three patients had infection at the surgical site. One patient had post-operative pneumonia leading to mortality. None of the patients had post-op haemorrhage. The surgeon volume and surgeon experience may have minimal contributing factor in post-operative morbidity, especially if there is availability of well-equipped ICU and imaging facilities, along with well-experienced personnel like oncosurgeon, anaesthesiologist, intensivist, radiologist, and nursing staff. There is a need of a multicentre study from Tier-II city hospitals/low-volume centres and high-volume centres to come with perioperative surgical outcomes following PD.

摘要

目前,胰十二指肠切除术(PD)被认为是一种针对壶腹周围肿瘤常见且可行的手术,但它仍是一种具有潜在发病率和死亡率的高风险手术。此前,一直强调需要高容量中心来实施诸如PD这样的专科手术。作者试图了解低容量中心与PD手术结果之间的关系。该研究在印度卡纳塔克邦的一家二级城市转诊医院进行。在4年时间里,即从2012年5月至2016年5月,共有37例疑似壶腹周围肿瘤的患者接受了根治性手术探查。在这37例患者中,26例接受了PD手术,其中经典的惠普尔切除术(=1例)或保留幽门的改良术(=25例)。11例患者无法进行切除,实施了胆道和胃引流手术。所有患者均按照我们中心用于胰腺切除的标准化术后护理方案进行治疗。我们记录了围手术期结果以及人口统计学数据、手术指征、PD手术的术前和术中因素。4例患者出现术后胰瘘。2例患者出现肝空肠吻合口漏。1例患者出现乳糜漏。3例患者手术部位发生感染。1例患者术后肺炎导致死亡。所有患者均未发生术后出血。外科医生的手术量和经验对术后发病率的影响可能最小,尤其是如果有设备完善的重症监护病房和影像设施,以及经验丰富的人员,如肿瘤外科医生、麻醉师、重症监护医生、放射科医生和护理人员。需要来自二级城市医院/低容量中心和高容量中心的多中心研究,以得出PD手术后的围手术期手术结果。