Pal Virendra K, Agrawal Ajai, Suman Suwarna, Pratap V B
Department of Ophthalmology, Regional Institute of Ophthalmology, Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India.
Middle East Afr J Ophthalmol. 2013 Oct-Dec;20(4):332-5. doi: 10.4103/0974-9233.120021.
The purpose of the study is to evaluate the long-term changes in intraocular pressure (IOP) after extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (PCIOL) implantation versus phacoemulsification with PCIOL implantation in otherwise normal cataract patients in India.
The study was conducted in the Department of Ophthalmology, King George's Medical College, Lucknow between August 2000 and August 2001. One hundred and seventeen eyes of 115 patients were included in the study. 84 patients were randomly selected for ECCE with PCIOL implantation (ECCE group) and 31 patients were selected for phacoemulsification with PCIOL implantation (Phaco group). IOP was measured pre-operatively and post-operatively, from the 1(st) month to the 12(th) month. Statistical significance was indicated by P > 0.05.
There was a mean fall in IOP of 2.70 mm Hg (19.74%) in the ECCE group and 2.74 mm Hg (20.57%) in the phaco group. The decrease in the mean post-operative IOP from baseline was statistically significant (P > 0.01) at the end of 2 months in both groups. There was no statistically significant difference in post-operative IOP at any visit between groups (P < 0.05, all post-operative visits). After 4(th) monthpost-operatively, the IOP was mostly stable, but it was significantly lower than the pre-operative IOP.
Significant IOP reduction may be expected after cataract surgery with either ECCE or phacoemulsification with IOL implantation. The lowering of IOP became statistically significant at about 2 months post-operatively, but became almost stable after the 4(th) month.
本研究旨在评估印度白内障患者在接受白内障囊外摘除术(ECCE)联合后房型人工晶状体(PCIOL)植入术与超声乳化白内障吸除术联合PCIOL植入术后眼压(IOP)的长期变化。
本研究于2000年8月至2001年8月在勒克瑙乔治国王医学院眼科进行。115例患者的117只眼纳入研究。84例患者被随机选择接受ECCE联合PCIOL植入术(ECCE组),31例患者被选择接受超声乳化白内障吸除术联合PCIOL植入术(超声乳化组)。术前及术后第1个月至第12个月测量眼压。P>0.05表示具有统计学意义。
ECCE组眼压平均下降2.70 mmHg(19.74%),超声乳化组眼压平均下降2.74 mmHg(20.57%)。两组术后2个月末平均眼压较基线的下降具有统计学意义(P>0.01)。两组在任何一次随访时的术后眼压均无统计学差异(P<0.05,所有术后随访)。术后第4个月后,眼压大多稳定,但显著低于术前眼压。
白内障手术无论是采用ECCE还是超声乳化联合人工晶状体植入,均可预期眼压显著降低。眼压降低在术后约2个月时具有统计学意义,但在第4个月后几乎稳定。