Chen Y J, Kurokawa T, Mitsudome A, Hanai T, Narazaki O, Ueda K
Eur J Pediatr. 1986 Dec;145(6):471-4. doi: 10.1007/BF02429045.
We assessed the usefulness of brainstem auditory evoked potentials (BAEPs) for differentiating types of degenerative diseases in children. The findings of BAEPs were abnormal in one out of two with polioencephalopathies and in seven of the eight with leukoencephalopathies, showing prolonged interpeak latencies of waves I-III, I-V or disappearance of wave components. On the other hand, normal responses were observed in four with corencephalopathies and one with spinocerebellopathy. The serial BAEPs in eight patients had deteriorated with progression of the clinical symptoms. These data on 16 children suggest that BAEPs are indeed a useful tool for monitoring pathophysiologic processes of neurodegenerative diseases.
我们评估了脑干听觉诱发电位（BAEPs）在鉴别儿童退行性疾病类型方面的实用性。在两例脑灰质炎患者中，有一例BAEPs结果异常；在八例白质脑病患者中，有七例异常，表现为I-III波、I-V波的峰间潜伏期延长或波成分消失。另一方面，四例大脑病患者和一例脊髓小脑病患者的反应正常。八名患者的系列BAEPs随着临床症状的进展而恶化。这16名儿童的数据表明，BAEPs确实是监测神经退行性疾病病理生理过程的有用工具。
