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孤独在精神障碍患者的内化污名与抑郁之间起中介作用。

Loneliness mediates the relationship between internalised stigma and depression among patients with psychotic disorders.

机构信息

I Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland

Educational Research Institute, Warsaw, Poland.

出版信息

Int J Soc Psychiatry. 2014 Dec;60(8):733-40. doi: 10.1177/0020764013513442. Epub 2013 Dec 16.

DOI:10.1177/0020764013513442
PMID:24346002
Abstract

BACKGROUND

Stigmatisation is a source of chronic stress and a major barrier to recovery for people with mental illnesses. The internalisation of stigma can have a negative impact on an individual's social relations and lead to feelings of loneliness and depression.

AIM

This research is aimed at testing the hypothesis that the internalised stigma of mental illness contributes to the intensification of depressive symptoms indirectly, through its impact on feelings of loneliness.

METHODS

A total of 110 individuals with diagnoses of psychotic disorders (International Classification of Diseases-10th Revision (ICD-10): F20-F29) were assessed with measures of internalised stigma, loneliness, depression, positive and negative symptoms and global functioning. The ordinary least squares regression was used for data analysis.

RESULTS

After adding loneliness to the regression model, the initially significant impact of internalised stigma on depressive symptoms disappeared. As expected, loneliness proved to be a full mediator in the relationship between stigma and depression.

CONCLUSION

The study findings provide useful insights into the mechanisms of the harmful effects of stigma on people with mental illness. Internalised stigma and loneliness should be considered important targets for interventions aiming to promote recovery.

摘要

背景

污名化是慢性压力的一个来源,也是精神疾病患者康复的主要障碍。污名内化会对个人的社会关系产生负面影响,并导致孤独和抑郁感。

目的

本研究旨在检验假设,即精神疾病的内化污名通过对孤独感的影响,间接地导致抑郁症状加剧。

方法

共评估了 110 名被诊断为精神病障碍的个体(国际疾病分类第 10 版(ICD-10):F20-F29),采用内化污名、孤独感、抑郁、阳性和阴性症状以及总体功能的测量方法。使用普通最小二乘法回归进行数据分析。

结果

在向回归模型中添加孤独感后,内化污名对抑郁症状的最初显著影响消失了。正如预期的那样,孤独感被证明是污名和抑郁之间关系的完全中介。

结论

研究结果为了解污名对精神疾病患者的有害影响的机制提供了有用的见解。内化污名和孤独感应被视为旨在促进康复的干预措施的重要目标。

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