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第一跖骨长度对糖尿病患者足部再溃疡风险的影响。

The influence of the length of the first metatarsal on the risk of reulceration in the feet of patients with diabetes.

作者信息

Molines-Barroso Raúl J, Lázaro-Martínez José L, Aragón-Sánchez Javier, García-Morales Esther, Carabantes-Alarcón David, Álvaro-Afonso Francisco Javier

机构信息

1Unidad de Pie Diabético, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.

出版信息

Int J Low Extrem Wounds. 2014 Mar;13(1):27-32. doi: 10.1177/1534734613516858. Epub 2013 Dec 18.

Abstract

Our aim was to identify the optimal diagnostic cutoff point on the scale of protrusion measurements of the first metatarsal (M1) to predict the probability of reulceration after metatarsal head resection in patients with diabetes mellitus. We conducted a prospective study of patients with diabetes who underwent resection of at least 1 metatarsal head in our department. After surgery, we measured the difference in length (protrusion) between the M1 and the longest of the 4 lesser metatarsals by radiographic view. The patients were divided into those in whom the M1 was the longest of the 5 metatarsals (group 1) and patients in whom at least one of the lesser metatarsals was longer than the M1 (group 2). They were followed-up for 12 months and were assessed for reulceration. Ninety-one patients were included in the present study: 43 (47%) in group 1 and 48 (53%) in group 2. In group 1, the longer the protrusion of M1 was, the higher the probability for reulceration (P < .001, 95% confidence interval = 0.813-0.997). In group 2, the shorter the protrusion of M1, the higher the probability for reulceration (P = .002, 95% confidence interval = 0.628-0.905). The optimal cutoff point for group 1 was 11 mm (sensitivity = 84.6%, specificity = 86.7%) for the probability of reulceration. In group 2, it was -7 mm (sensitivity = 81.8%, specificity = 65.4%). These results suggest that M1 protrusion is an optimum prognostic indicator for reulceration and could be recommended for detecting patients at risk of reulceration after surgery.

摘要

我们的目的是确定第一跖骨(M1)突出测量值的最佳诊断切点,以预测糖尿病患者跖骨头切除术后再溃疡的可能性。我们对在我科接受至少1个跖骨头切除的糖尿病患者进行了一项前瞻性研究。术后,我们通过X线片测量M1与4根较小跖骨中最长者之间的长度差异(突出度)。患者被分为M1是5根跖骨中最长的一组(第1组)和至少有一根较小跖骨比M1长的患者(第2组)。对他们进行了12个月的随访,并评估是否发生再溃疡。本研究共纳入91例患者:第1组43例(47%),第2组48例(53%)。在第1组中,M1突出度越长,再溃疡的可能性越高(P<0.001,95%置信区间=0.813 - 0.997)。在第2组中,M1突出度越短,再溃疡的可能性越高(P = 0.002,95%置信区间=0.628 - 0.905)。第1组再溃疡可能性的最佳切点为11 mm(敏感性=84.6%,特异性=86.7%)。在第2组中,为 - 7 mm(敏感性=81.8%,特异性=65.4%)。这些结果表明,M1突出度是再溃疡的最佳预后指标,可用于检测术后有再溃疡风险的患者。

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