Unidad de Pie Diabético, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.
Diabet Med. 2013 Aug;30(8):973-6. doi: 10.1111/dme.12202. Epub 2013 Apr 20.
To analyse the risk of reulceration caused by the transfer of lesions in patients with diabetes, undergoing resection of at least one metatarsal head.
A total of 119 patients with diabetes from the Diabetic Foot Unit (Complutense University, Madrid, Spain), who underwent resection of at least one metatarsal head were analysed prospectively from November 2006 to December 2011 to assess reulceration in the other metatarsal head.
Seven patients were excluded for being subjected to a pan-metatarsal head resection and 11 patients dropped out. During a median follow-up period of 13.1 months (interquartile range 6.1-22.8 months), 41% of patients suffered from reulcerations. Reulceration frequency in patients operated on the 1st, 2nd, 3rd, 4th, 5th and several metatarsal heads was 9 (69%), 8 (44%), 12 (52%), 2 (25%), 6 (19%) and 4 (50%) events, respectively. The Cox regression model showed hazard ratios that were significant for the location of the metatarsal resection. The first metatarsal showed the highest risk for reulceration (hazard ratio 3.307; 1.472-7.430) and the fifth metatarsal showed the lowest risk (hazard ratio 0.339; 0.138-0.832).
Reulceration is a frequent event following resection of a metatarsal head and should be regarded as an implicit complication of the intervention. The location of the resection determines the risk of reulceration, which is highest for patients operated on the first metatarsal head and lowest for patients operated on the fifth metatarsal head.
分析糖尿病患者在切除至少一个跖骨头后,因病变转移而导致溃疡复发的风险。
2006 年 11 月至 2011 年 12 月,对来自西班牙马德里 Complutense 大学糖尿病足科的 119 名接受至少一个跖骨头切除术的糖尿病患者进行前瞻性分析,以评估其他跖骨头的溃疡复发情况。
7 名患者因接受全跖骨头切除术而被排除,11 名患者脱落。在中位数为 13.1 个月(四分位距 6.1-22.8 个月)的随访期间,41%的患者出现溃疡复发。在接受第 1、2、3、4、5 跖骨头和多个跖骨头切除术的患者中,溃疡复发的频率分别为 9(69%)、8(44%)、12(52%)、2(25%)、6(19%)和 4(50%)事件。Cox 回归模型显示,跖骨切除部位的风险比具有统计学意义。第一跖骨的溃疡复发风险最高(风险比 3.307;1.472-7.430),而第五跖骨的溃疡复发风险最低(风险比 0.339;0.138-0.832)。
切除跖骨头后溃疡复发是一种常见事件,应视为该干预的一种隐含并发症。切除部位决定了溃疡复发的风险,第一跖骨切除的风险最高,第五跖骨切除的风险最低。