Department of Neurosurgery, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Neurological Intervention and Imaging Service of Western Australia, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Global Spine J. 2012 Sep;2(3):169-74. doi: 10.1055/s-0032-1315451. Epub 2012 Aug 24.
Vertebral hemangiomas are benign lesions accounting for 2 to 3% of all spinal tumors. They are usually asymptomatic and found incidentally on imaging. Uncommonly, vertebral hemangiomas with significant epidural extension can result in radiculopathy or spinal cord compression. Decompressive surgery with or without stabilization is often required when neurological deficits are present. However, surgery can be associated with massive hemorrhage as these tumors are hypervascular. Preoperative embolization and sclerotherapy are well-known management strategies used to minimize intraoperative bleeding and improve symptoms. Recently, the use of sclerosants such as ethanol has decreased, due to reported complications such as Brown-Sequard syndrome. We describe the use of sodium tetradecyl sulfate (Fibro-Vein™, STD Pharmaceutical, Hereford, UK) as an effective alternative to ethanol in the preoperative management of vertebral hemangiomas. To our knowledge, this has not been previously reported. In three patients, we demonstrated minimal intraoperative blood loss using a combination of preoperative embolization of arterial feeders and sclerotherapy with sodium tetradecyl sulfate to control and secure venous drainage. No patients developed complications related to the procedure. In addition to minimal blood loss, a clear dissection plane was also noted intraoperatively.
椎体血管瘤是良性病变,占所有脊柱肿瘤的 2%至 3%。它们通常无症状,在影像学检查中偶然发现。不常见的是,具有显著硬膜外延伸的椎体血管瘤可导致神经根病或脊髓压迫。当存在神经功能缺损时,通常需要减压手术加或不加稳定术。然而,由于这些肿瘤富含血管,手术可能会导致大量出血。术前栓塞和硬化疗法是众所周知的管理策略,用于最大限度地减少术中出血并改善症状。最近,由于报道的并发症,如 Brown-Sequard 综合征,乙醇等硬化剂的使用减少。我们描述了使用十四烷基硫酸钠(Fibro-Vein™,STD Pharmaceutical,Hereford,英国)作为乙醇在椎体血管瘤术前管理中的有效替代品。据我们所知,这尚未有报道。在 3 名患者中,我们通过动脉供血的术前栓塞和十四烷基硫酸钠硬化疗法的联合应用,证明了术中出血量最小,以控制和确保静脉引流。没有患者发生与该手术相关的并发症。除了出血量少,术中还注意到清晰的解剖平面。