Postevka Eugene
Midwestern University Nurse Anesthesia Program, Glendale, AZ, USA.
AANA J. 2013 Oct;81(5):386-8.
Myasthenia gravis is an autoimmune neuromuscular disorder that causes the destruction and overall decrease in functional acetylcholine receptors at the neuromuscular junction. The resultant respiratory and cardiovascular implications are a primary cause of mortality; therefore, a complete and comprehensive understanding of this disorder is vital for the anesthesia provider. The case presented demonstrates the anesthetic challenges involved, with a focus on the overall approach, pharmacologic considerations, physiological changes, and an emphasis on preoperative optimization.
重症肌无力是一种自身免疫性神经肌肉疾病，会导致神经肌肉接头处功能性乙酰胆碱受体的破坏和总体减少。由此产生的呼吸和心血管方面的影响是死亡的主要原因；因此，全面、透彻地了解这种疾病对麻醉医生至关重要。所呈现的病例展示了其中涉及的麻醉挑战，重点在于总体方法、药物考量、生理变化，并强调术前优化。
