Ishizaka Shunsuke, Shimizu Tadashi, Ryu Nobutoshi
Department of Neurosurgery, Juzenkai Hospital , Nagasaki , Japan.
Brain Inj. 2014;28(3):374-7. doi: 10.3109/02699052.2013.864422. Epub 2013 Dec 19.
Although Duret haemorrhage of the brainstem caused by descending transtentorial herniation is considered fatal, a few cases have been reported to have good outcome. Moreover, most patients with Duret haemorrhage have severe primary brain injury and the potential outcome of those with mild primary brain injury remains unknown.
This study reports the case of a patient presenting with Duret haemorrhage caused by an idiopathic subdural haematoma who demonstrated dramatic recovery. The patient presented with a low Glasgow Coma Scale score and bilateral oculomotor palsy on admission. Pre-operative CT revealed a large subdural haematoma and Duret haemorrhage of the mid-brain. The subdural haematoma was immediately evacuated under local anaesthesia and the patient demonstrated dramatic post-operative recovery, with no residual quadriparesis and minimal cognitive dysfunction. Interestingly, only bilateral oculomotor palsy persisted. This indicates that Duret haemorrhage restricted to the central portion of the mid-brain without severe primary brain injury has good prognosis.
Therefore, patients with Duret haemorrhage of the mid-brain caused by simple subdural haematoma presenting with bilateral oculomotor palsy, including bilateral pupillary dilation, may not always have a poor prognosis.
尽管由下行性小脑幕切迹疝引起的脑干杜雷氏出血被认为是致命的,但已有少数病例报告预后良好。此外,大多数杜雷氏出血患者有严重的原发性脑损伤,而轻度原发性脑损伤患者的潜在预后仍不清楚。
本研究报告了一例由特发性硬膜下血肿引起杜雷氏出血的患者,该患者显示出显著的恢复。患者入院时格拉斯哥昏迷量表评分低且双侧动眼神经麻痹。术前CT显示巨大硬膜下血肿和中脑杜雷氏出血。硬膜下血肿在局部麻醉下立即清除,患者术后恢复显著,无残留四肢瘫痪且认知功能障碍轻微。有趣的是,仅双侧动眼神经麻痹持续存在。这表明局限于中脑中央部分且无严重原发性脑损伤的杜雷氏出血预后良好。
因此,由单纯硬膜下血肿引起的中脑杜雷氏出血且伴有双侧动眼神经麻痹(包括双侧瞳孔散大)的患者,预后不一定总是很差。