阿司匹林的使用与黑色素瘤风险：文献综述。

Aspirin use and melanoma risk: a review of the literature.

机构信息

David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

出版信息

J Am Acad Dermatol. 2014 Jan;70(1):187-91. doi: 10.1016/j.jaad.2013.09.045.

DOI:10.1016/j.jaad.2013.09.045

PMID:24355265

Abstract

In view of the increasing incidence of melanoma, it is critical to find effective preventive approaches. Contradictory evidence has been reported with regard to the possible association of aspirin use and the risk of melanoma. We review these studies and seek to elucidate the mechanism by which aspirin may produce a chemoprotective effect against melanoma.

摘要

鉴于黑色素瘤发病率的不断上升，寻找有效的预防方法至关重要。关于阿司匹林的使用与黑色素瘤风险之间可能存在的关联，已有相互矛盾的证据报道。我们对这些研究进行了综述，并试图阐明阿司匹林可能对黑色素瘤产生化学预防作用的机制。