Guldbrandt Louise Mahncke, Fenger-Grøn Morten, Folkersen Birgitte Holst, Rasmussen Torben Riis, Vedsted Peter
Center for Forskning i Cancerdiagnostik i Praksis, Forskningsenheden for Almen Praksis, Aarhus Universitet, Bartholins Allé 2, 8000 Aarhus C, Denmark.
Dan Med J. 2013 Dec;60(12):A4738.
Lung cancer (LC) is the most common cause of cancer death in Denmark, and triaging patients through fast-track diagnostic pathways is recommended to improve patient outcome. Data on the most efficient triage organisation of such pathways are limited. The aim of this study was to test a strategy of a straight-to-test model for patients referred to the fast-track pathway. Outcomes were number of computed tomographies (CT) performed, use of specialist time and staff acceptability.
We performed a randomised controlled study enrolling 493 patients who were referred from general practice to fast-track LC evaluation (1 January-1 December 2012). Half of the patients were randomly assigned to the intervention and went straight to a chest CT before chest-physician evaluation. Time was measured for patients at random days. Acceptability was examined in a focus group interview.
In the intervention group, 95.5% of patients had a CT performed compared with 97.2% in the control group. There was no difference in the number of CTs between the groups (risk difference (RD) = 1.3% (95% confidence interval (CI): 4.4-2.0; p = 0.454)). In the intervention group, chest-physician time was 13.3 min. (min.-max.: 7.7-19.5 min.) lower per referred patient than in the control group.
Giving general practitioners direct access to a CT did not change the number of CTs performed and significantly reduced chest-physician time per patient. In addition, the strategy was associated with high levels of staff acceptability.
The project was supported by the Danish Cancer Research Foundation, the Danish Cancer Society and the Novo Nordisk Foundation.
ClinicalTrials.gov: NCT01779726.
肺癌是丹麦癌症死亡的最常见原因,建议通过快速诊断途径对患者进行分流以改善患者预后。关于此类途径最有效的分流组织的数据有限。本研究的目的是测试一种针对转诊至快速通道的患者的直接检测模型策略。结果指标为计算机断层扫描(CT)检查的数量、专科医生时间的使用情况以及工作人员的可接受性。
我们进行了一项随机对照研究,纳入了493名从全科医疗转诊至快速通道进行肺癌评估的患者(2012年1月1日至12月31日)。一半患者被随机分配至干预组,在胸部医生评估前直接进行胸部CT检查。在随机的日子里对患者进行时间测量。通过焦点小组访谈检查可接受性。
干预组中95.5%的患者进行了CT检查,对照组为97.2%。两组之间的CT检查数量没有差异(风险差异(RD)=1.3%(95%置信区间(CI):4.4 - 2.0;p = 0.454))。干预组中,每位转诊患者的胸部医生问诊时间比对照组少13.3分钟(最小值 - 最大值:7.7 - 19.5分钟)。
让全科医生直接开具CT检查并未改变CT检查的数量,且显著减少了每位患者的胸部医生问诊时间。此外,该策略具有较高的工作人员可接受性。
该项目由丹麦癌症研究基金会、丹麦癌症协会和诺和诺德基金会资助。
ClinicalTrials.gov:NCT01779726。