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原位肝移植联合改良背驮式技术后下腔静脉扭转的血管内治疗:一期支架置入术

Endovascular treatment with primary stenting of inferior cava vein torsion following orthotopic liver transplantation with modified piggyback technique.

机构信息

Dipartimento di Radiologia e Radiologia Interventistica, IRCCS Azienda Ospedaliera ed Universitaria San Martino, IST-Istituto Nazionale per la Ricerca sul Cancro, Monoblocco 1-Fondi, Largo Rosanna Benzi 10, 16132, Genoa, Italy,

出版信息

Radiol Med. 2014 Mar;119(3):183-8. doi: 10.1007/s11547-013-0325-4. Epub 2013 Dec 20.

DOI:10.1007/s11547-013-0325-4
PMID:24356944
Abstract

PURPOSE

This study was undertaken to evaluate primary stenting in patients with inferior vena cava torsion after orthotopic liver transplantation performed with modified piggyback technique.

MATERIALS AND METHODS

From November 2003 to October 2010, six patients developed clinical, laboratory and imaging findings suggestive of caval stenosis, after a mean period of 21 days from an orthotopic liver transplantation performed with modified piggyback technique. Vena cavography showed stenosis due to torsion of the inferior vena cava at the anastomoses and a significant caval venous pressure gradient. All patients were treated with primary stenting followed by in-stent angioplasty in three cases.

RESULTS

In all patients, the stents were successfully positioned at the caval anastomosis and the venous gradient pressure fell from a mean value of 10 to 2 mmHg. Signs and symptoms resolved in all six patients. One patient died 3 months after stent placement due to biliary complications. No evidence of recurrence or complications was noted during the follow-up (mean 49 months).

CONCLUSIONS

Primary stenting of inferior vena cava stenosis due to torsion of the anastomoses in patients receiving orthotopic liver transplantation with modified piggyback technique is a safe, effective and durable treatment.

摘要

目的

本研究旨在评估改良背驮式肝移植术后下腔静脉扭转患者的初次支架置入治疗效果。

材料与方法

2003 年 11 月至 2010 年 10 月,6 例患者在改良背驮式肝移植术后 21 天出现下腔静脉吻合口扭转导致狭窄的临床、实验室和影像学表现,下腔静脉造影显示吻合口狭窄,下腔静脉压力梯度显著升高。所有患者均采用初次支架置入治疗,其中 3 例随后进行了支架内血管成形术。

结果

所有患者的支架均成功定位在下腔静脉吻合口,静脉压力梯度从平均 10mmHg 降至 2mmHg。所有 6 例患者的症状和体征均得到缓解。1 例患者在支架置入 3 个月后因胆系并发症死亡。在平均 49 个月的随访中,未发现再狭窄或并发症的证据。

结论

改良背驮式肝移植术后下腔静脉吻合口扭转导致狭窄的初次支架置入是一种安全、有效且持久的治疗方法。

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Inferior Vena Cava Constriction After Liver Transplantation Is a Severe Complication Requiring Individually Adapted Treatment: Report of a Single-Center Experience.肝移植术后下腔静脉狭窄是一种需要个体化治疗的严重并发症:单中心经验报告。
Ann Transplant. 2020 Aug 4;25:e925194. doi: 10.12659/AOT.925194.
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Vascular complications following liver transplantation: A literature review of advances in 2015.

本文引用的文献

1
Diagnostic role of colour Doppler US at 1-year follow-up after orthotopic liver transplantation.彩色多普勒超声在原位肝移植 1 年后随访中的诊断作用。
Radiol Med. 2010 Dec;115(8):1304-13. doi: 10.1007/s11547-010-0562-8. Epub 2010 Jun 23.
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Vascular complications following adult piggyback liver transplantation with end-to-side cavo-cavostomy: a single-center experience.成人背驮式肝移植行腔静脉端侧吻合术后的血管并发症:单中心经验
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Stent migration complicating treatment of inferior vena cava stenosis after orthotopic liver transplantation.
肝移植后的血管并发症:2015年进展的文献综述
World J Hepatol. 2016 Jan 8;8(1):36-57. doi: 10.4254/wjh.v8.i1.36.
支架移位使原位肝移植后下腔静脉狭窄的治疗复杂化。
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Treatment of hepatic venous outflow obstruction after piggyback liver transplantation.背驮式肝移植术后肝静脉流出道梗阻的治疗
Radiology. 2005 Jul;236(1):352-9. doi: 10.1148/radiol.2361040327. Epub 2005 Jun 13.
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Hepatic vein stenosis after living donor liver transplantation: evaluation with Doppler US.
Radiology. 2003 Dec;229(3):806-10. doi: 10.1148/radiol.2293020700. Epub 2003 Oct 23.
6
Management of hepatic venous obstruction after split-liver transplantation.活体肝移植术后肝静脉梗阻的处理
Pediatr Transplant. 2000 Nov;4(4):322-7. doi: 10.1034/j.1399-3046.2000.00124.x.
7
Treatment of inferior vena cava anastomotic stenoses with the Wallstent endoprosthesis after orthotopic liver transplantation.原位肝移植后应用Wallstent血管内支架治疗下腔静脉吻合口狭窄
J Vasc Interv Radiol. 1999 Jan;10(1):17-22. doi: 10.1016/s1051-0443(99)70003-5.
8
Primary Gianturco stent placement for inferior vena cava abnormalities following liver transplantation.肝移植术后下腔静脉异常的原发性Gianturco支架置入术
J Vasc Interv Radiol. 2000 Feb;11(2 Pt 1):177-87. doi: 10.1016/s1051-0443(07)61462-6.
9
Specific vascular complications of orthotopic liver transplantation with preservation of the retrohepatic vena cava: review of 1361 cases.保留肝后下腔静脉的原位肝移植的特定血管并发症:1361例病例回顾
Transplantation. 1999 Sep 15;68(5):646-50. doi: 10.1097/00007890-199909150-00009.
10
Endovascular treatment of hepatic venous outflow obstruction after piggyback technique liver transplantation.
Transplantation. 1999 Aug 15;68(3):446-9. doi: 10.1097/00007890-199908150-00018.