自发性眼上静脉血栓形成：一种罕见的疾病，可能产生毁灭性后果。
Spontaneous superior ophthalmic vein thrombosis: a rare entity with potentially devastating consequences.
作者信息
Lim L H, Scawn R L, Whipple K M, Oh S R, Lucarelli M J, Korn B S, Kikkawa D O
机构信息
1] Division of Oculofacial Plastic and Reconstructive Surgery, UCSD Shiley Eye Center, La Jolla, CA, USA [2] Oculoplastic Service, Singapore National Eye Center, Singapore, Singapore.
Division of Oculofacial Plastic and Reconstructive Surgery, UCSD Shiley Eye Center, La Jolla, CA, USA.
出版信息
Eye (Lond). 2014 Mar;28(3):348-51. doi: 10.1038/eye.2013.273. Epub 2013 Dec 20.
PURPOSE
Spontaneous superior ophthalmic vein thrombosis (SOVT) is a rare entity. We describe three patients with spontaneous ophthalmic vein thrombosis, each with various risk factors.
PATIENTS AND METHODS
A retrospective review of three patients with a diagnosis of superior ophthalmic vein thrombosis. Clinical characteristics, radiographic features, management techniques and outcomes are described.
RESULTS
All patients presented with unilateral painful proptosis. Two patients had intact light perception, whereas one patient presented with absent light perception. All patients had identifiable risk factors for thrombosis, which included sickle cell trait, hereditary hemorrhagic telangectasia and colon cancer with recurrent deep vein thrombosis. Anticoagulation was initiated in two patients. Resolution of proptosis was seen in all patients, with no recovery of vision in one patient.
CONCLUSIONS
Risk factors for spontaneous superior ophthalmic vein thrombosis are multifactorial. MRI and MRV confirm the diagnosis of SOVT. Despite urgent intervention devastating visual loss may occur.
目的
自发性眼上静脉血栓形成（SOVT）是一种罕见的病症。我们描述了三例自发性眼静脉血栓形成患者，每例都有不同的危险因素。
患者与方法
对三例诊断为眼上静脉血栓形成的患者进行回顾性研究。描述了其临床特征、影像学特征、治疗技术及结果。
结果
所有患者均表现为单侧疼痛性眼球突出。两名患者光感正常，而一名患者无光感。所有患者均有可识别的血栓形成危险因素，包括镰状细胞性状、遗传性出血性毛细血管扩张症和患有复发性深静脉血栓形成的结肠癌。两名患者开始抗凝治疗。所有患者的眼球突出均得到缓解，一名患者视力未恢复。
结论
自发性眼上静脉血栓形成的危险因素是多因素的。MRI和MRV可确诊SOVT。尽管进行了紧急干预，仍可能发生严重的视力丧失。
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