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以自身免疫和感染性疾病为并发症的上腔静脉血栓形成伴完全视力丧失。

Superior Ophthalmic Vein Thrombosis with Complete Loss of Vision as a Complication of Autoimmune and Infective Conditions.

机构信息

a Department of Ophthalmology , University Hospital Centre Zagreb , Zagreb , Croatia.

出版信息

Ocul Immunol Inflamm. 2018;26(7):1066-1068. doi: 10.1080/09273948.2017.1313433. Epub 2017 May 24.

Abstract

PURPOSE

To present our experience in the management of superior ophthalmic vein thrombosis (SOVT), which is a rare, but extremely serious condition if not recognized and managed promptly and appropriately.

METHODS

Two patients with septic and aseptic SOVT are presented. Clinical characteristics, radiographic features, management techniques, and outcomes are described.

RESULTS

In the first case thrombosis occurred as a complication of functional endoscopic sinus surgery. In the second case thrombosis occurred as a complication of untreated inflammatory bowel disease: ulcerative colitis. Both cases resulted with permanent unilateral blindness.

CONCLUSION

SOVT is a rare entity. There are no guidelines, just recommendations for disease management. Based on our experience, broad-spectrum intravenous antibiotic, anticoagulation, and steroid therapy should be promptly introduced and if needed surgical intervention. SOVT can lead to devastating complications which include permanent loss of vision and in some cases a fatal outcome.

摘要

目的

介绍我们在治疗上腔静脉血栓形成(SOVT)方面的经验,SOVT 虽然罕见,但如果不能及时、恰当地识别和处理,后果将非常严重。

方法

报告 2 例感染性和非感染性 SOVT 患者。描述了其临床特征、影像学特征、处理技术和结局。

结果

第 1 例患者是功能性内窥镜鼻窦手术后发生血栓形成,第 2 例患者是未经治疗的炎症性肠病(溃疡性结肠炎)发生血栓形成。这两例患者均导致单侧永久性失明。

结论

SOVT 是一种罕见的疾病。目前没有针对该病的管理指南,只有一些推荐意见。根据我们的经验,应迅速采用广谱静脉内抗生素、抗凝和类固醇治疗,如果需要,还应进行手术干预。SOVT 可导致严重并发症,包括永久性失明,在某些情况下还会导致致命后果。

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