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巴西一只圈养西部低地大猩猩(Gorilla gorilla gorilla)感染肠炎沙门氏菌婴儿亚种引发出血性结肠炎。

Hemorrhagic colitis associated with Salmonella enterica serotype Infantis infection in a captive western lowland gorilla (Gorilla gorilla gorilla) in Brazil.

作者信息

Paixão Tatiane A, Malta Marcelo C C, Soave Semíramis A, Tinoco Herlandes P, Costa Maria E L T, Pessanha Angela T, Silva Rodrigo O S, Coura Fernanda M, Costa Luciana F, Turchetti Andreia P, Lobato Francisco C F, Melo Marilia M, Heinemann Marcos B, Santos Renato L

机构信息

Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

出版信息

J Med Primatol. 2014 Apr;43(2):118-21. doi: 10.1111/jmp.12094. Epub 2013 Dec 23.

DOI:10.1111/jmp.12094
PMID:24359673
Abstract

BACKGROUND

Enteric diseases are among the most common causes of morbidity and mortality in gorillas, and it is often caused by bacteria.

METHODS

A thirteen-year-old captive female western lowland gorilla (Gorilla gorilla gorilla) developed hemorrhagic diarrhea. Despite the treatment, the animal died 7 days after the onset of clinical signs. The animal was submitted to a thorough pathological and microbiological evaluation.

RESULTS

Pathologic examination revealed a severe acute hemorrhagic colitis, neutrophilic splenitis, glomerulitis, and interstitial pneumonia. Salmonella enterica serotype Infantis was isolated from a mesenteric lymph node.

CONCLUSION

A diagnosis of hemorrhagic colitis associated with Salmonella enterica serotype Infantis was established.

摘要

背景

肠道疾病是大猩猩发病和死亡的最常见原因之一,且通常由细菌引起。

方法

一只13岁的圈养雌性西部低地大猩猩(Gorilla gorilla gorilla)出现了出血性腹泻。尽管进行了治疗,但该动物在出现临床症状7天后死亡。对该动物进行了全面的病理和微生物学评估。

结果

病理检查显示严重的急性出血性结肠炎、嗜中性粒细胞性脾炎、肾小球肾炎和间质性肺炎。从肠系膜淋巴结中分离出肠炎沙门氏菌婴儿亚种。

结论

确诊为与肠炎沙门氏菌婴儿亚种相关的出血性结肠炎。

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First known case of paediatric inflammatory bowel disease in a western lowland gorilla may be linked to a familial mutation in the gene.西部低地大猩猩首次出现小儿炎症性肠病病例,可能与该基因的家族突变有关。
Gut. 2020 Jun;69(6):1153-1154. doi: 10.1136/gutjnl-2019-319051. Epub 2019 Jun 21.
2
Draft Genome Sequences of Two Salmonella enterica Serotype Infantis Strains Isolated from a Captive Western Lowland Gorilla (Gorilla gorilla gorilla) and a Cohabitant Black and White Tegu (Tupinambis merianae) in Brazil.从巴西一只圈养的西部低地大猩猩(Gorilla gorilla gorilla)和同居的黑白泰加蜥蜴(Tupinambis merianae)中分离出的两株肠炎沙门氏菌婴儿亚种菌株的基因组序列草图
Genome Announc. 2016 Jan 21;4(1):e01590-15. doi: 10.1128/genomeA.01590-15.