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[Nitrid oxide, levosimendan and sildenafile in a patient with right ventricle dysfunction and severe pulmonary hypertension after cardiac surgery].

作者信息

Aleixandre L, Cortell J, Vicente R, Herrera P, Loro J M, Valera F

机构信息

Servicio de Anestesiología y Reanimación, Hospital La Fe, Valencia, España.

Servicio de Anestesiología y Reanimación, Hospital La Fe, Valencia, España.

出版信息

Rev Esp Anestesiol Reanim. 2014 Nov;61(9):513-6. doi: 10.1016/j.redar.2013.09.020. Epub 2013 Dec 19.

Abstract

Pulmonary hypertension (PHT) and the resulting right ventricle dysfunction are important risk factors in patients who undergo cardiac surgery. The treatment of PHT and right ventricle dysfunction should be focused on maintaining the correct right ventricle after load, improving right ventricle function and reducing the right ventricle pre-load and therefore reducing pulmonary vascular resistance by means of vasodilators. A combined therapy of vasodilators and medicines which have different mechanisms of action, is becoming an option for the treatment of PHT. We present a 65 year old woman that suffered from mitral regurgitation, aortic valve disease, tricuspid and ascending aortic dilation with 115mmHg of pulmonary artery pressure (by ultrasound evaluation). The patient was operated on of mitral, aortic valve and tricuspid plastia and proximal aortic artery plastia as well. Previosly to surgery the patient suffered right ventricle dysfunction and PHT and was treated with nitric oxide, intravenous sildenafil and levosimendan. Subsequent evolution was satisfactory, PHT being controlled, without arterial hypotension nor respiratory alterations.

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