Jones S W
Neurosci Lett. 1987 Mar 9;74(3):309-14. doi: 10.1016/0304-3940(87)90315-6.
C cells of bullfrog sympathetic ganglia have an M-current similar to that of the larger B cells. However, the M-current of C cells is much less sensitive to muscarinic agonists. The M-current of C cells is blocked by barium and by LHRH (mammalian luteinizing hormone-releasing hormone). LHRH sometimes also decreases a different conductance, with an extrapolated reversal potential near 0 mV. These results demonstrate that the coupling of receptors to ion channels can vary between cell types, even within a single ganglion.
牛蛙交感神经节的C细胞具有与较大的B细胞类似的M电流。然而,C细胞的M电流对毒蕈碱激动剂的敏感性要低得多。C细胞的M电流可被钡和促黄体生成素释放激素(哺乳动物促黄体激素释放激素)阻断。促黄体生成素释放激素有时也会降低另一种不同的电导,其推断的反转电位接近0毫伏。这些结果表明,即使在单个神经节内,受体与离子通道的偶联在不同细胞类型之间也会有所不同。