Stara Alzbeta, Steinbach Christoph, Wlasow Teresa, Gomulka Piotr, Ziemok Elzbieta, Machova Jana, Velisek Jozef
Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, University of South Bohemia, Ceske Budejovice, Czech Republic.
Faculty of Environmental Sciences and Fisheries, University of Warmia and Mazury Olsztyn, Poland.
Neuro Endocrinol Lett. 2013;34 Suppl 2:37-42.
The aim of this study was to assess the effect of pesticide Fury 10 EW, containing zeta-cypermethrin 100 g.l-1, on common carp (Cyprinus carpio L.).
The toxicity tests were performed on common carp according to OECD 203 methodologies. The common carp were exposed to Fury 10 EW at concentrations, 5, 7, 10, 50 and 100 μg.l-1 for 96 h and compared to common carp in a non-treated control group. Acute toxicity tests were detected value 96hLC50=13.8 µg.l-1. On the basis of the results was assessed the effect on the hematological profile, oxidative stress parameters, and antioxidants biomarkers in tissues, in another acute test.
The observed 96hLC50 value of Fury 10 EW was 13.8 μg.l-1. A significantly lower large lymphocyte and monocyte count, and a significantly greater number of segmented eosinophil granulocyte and higher hematocrit was found in the pesticide-exposed common carp compared to controls. Oxidative damage was not detected in the experimental common carp, however there were significant differences from control in superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) in tissue after acute exposure to 13.8 μg.l-1 Fury 10 EW.
Zeta-cypermethrin as Fury 10 EW was classified as a substance highly toxic to fish. The hematological profile well oxidative stress parameters and antioxidant defensive systems provide important information about the internal environment of organisms. There is a lack of experimental results about the effects of zeta-cypermethrin on fish in the literature.
本研究旨在评估含有100 g.l-1高效氯氰菊酯的农药富锐10 EW对鲤鱼（Cyprinus carpio L.）的影响。
根据经合组织203方法对鲤鱼进行毒性试验。将鲤鱼暴露于浓度为5、7、10、50和100 μg.l-1的富锐10 EW中96小时，并与未处理的对照组鲤鱼进行比较。急性毒性试验检测值96hLC50 = 13.8 μg.l-1。基于这些结果，在另一项急性试验中评估了其对血液学指标、氧化应激参数以及组织中抗氧化生物标志物的影响。
观察到富锐10 EW的96hLC50值为13.8 μg.l-1。与对照组相比，暴露于农药的鲤鱼中大型淋巴细胞和单核细胞计数显著降低，而分叶嗜酸性粒细胞数量显著增加且血细胞比容更高。在实验鲤鱼中未检测到氧化损伤，然而，急性暴露于13.8 μg.l-1富锐10 EW后，组织中的超氧化物歧化酶（SOD）、过氧化氢酶（CAT）和谷胱甘肽还原酶（GR）与对照组存在显著差异。
作为富锐10 EW的高效氯氰菊酯被归类为对鱼类剧毒的物质。血液学指标、氧化应激参数和抗氧化防御系统为生物体内部环境提供了重要信息。文献中缺乏关于高效氯氰菊酯对鱼类影响的实验结果。
